Baculovirus LIFR Recombinant Protein – Cat# MBS206155

LIFR Baculovirus Recombinant Protein

Name: LIFR Recombinant Protein; Baculovirus; MyBioSource
Brand: MyBioSource
SKU: MBS206155
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206155

LIFR, also known as leukemia inhibitory factor receptor, is the receptor for leukemia inhibitory factor, a pleiotropic cytokine affecting the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR plays an… More details

$230 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LIFR, Recombinant Protein

Full Product Name

LIFR, 45-833aa, Human, His tag, Baculovirus

Product Gene Name

LIFR recombinant protein

Product Synonym Names

Leukemia inhibitory factor receptor; LIFR; CD118; LIF-R; SJS2; STWS; SWS

Sequence

ADPQKKGAPH DLKCVTNNLQ VWNCSWKAPS GTGRGTDYEV CIENRSRSCY QLEKTSIKIP ALSHGDYEIT INSLHDFGSS TSKFTLNEQN VSLIPDTPEI LNLSADFSTS TLYLKWNDRG SVFPHRSNVI WEIKVLRKES MELVKLVTHN TTLNGKDTLH HWSWASDMPL ECAIHFVEIR CYIDNLHFSG LEEWSDWSPV KNISWIPDSQ TKVFPQDKVI LVGSDITFCC VSQEKVLSAL IGHTNCPLIH LDGENVAIKI RNISVSASSG TNVVFTTEDN IFGTVIFAGY PPDTPQQLNC ETHDLKEIIC SWNPGRVTAL VGPRATSYTL VESFSGKYVR LKRAEAPTNE SYQLLFQMLP NQEIYNFTLN AHNPLGRSQS TILVNITEKV YPHTPTSFKV KDINSTAVKL SWHLPGNFAK INFLCEIEIK KSNSVQEQRN VTIKGVENSS YLVALDKLNP YTLYTFRIRC STETFWKWSK WSNKKQHLTT EASPSKGPDT WREWSSDGKN LIIYWKPLPI NEANGKILSY NVSCSSDEET QSLSEIPDPQ HKAEIRLDKN DYIISVVAKN SVGSSPPSKI ASMEIPNDDL KIEQVVGMGK GILLTWHYDP NMTCDYVIKW CNSSRSEPCL MDWRKVPSNS TETVIESDEF RPGIRYNFFL YGCRNQGYQL LRSMIGYIEE LAPIVAPNFT VEDTSADSIL VKWEDIPVEE LRGFLRGYLF YFGKGERDTS KMRVLESGRS DIKVKNITDI SQKTLRIADL QGKTSYHLVL RAYTDGGVGP EKSMYVVTKE NSHHHHHH

Host

Baculovirus

Form/Format

Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Absorbance at 280nm) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

90.5kDa (798aa) 100-150KDa (SDS-PAGE under reducing conditions.)

OMIM

X61615 mRNA

3D Structure

ModBase 3D Structure for P42702

Antigen Species

Human

Tag Information

His-tag

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Product Categories/Family for LIFR recombinant protein

Immunology

Applications Tested/Suitable for LIFR recombinant protein

SDS-PAGE

Product References and Citations for LIFR recombinant protein

Gearing DP., et al. (1991) EMBO J. 10:2839-2848.; Cheng JG., et al. (2001) Proc Nati Acad Sci USA 98:8680-8685.

Other Notes

Small volumes of LIFR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LIFR purchase

MBS206155 is a recombinant protein targeting LIFR. Also known as LIFR, 45-833aa, Human, His tag, Baculovirus. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for LIFR. It may not necessarily be applicable to this product.

NCBI GI #

4504993

NCBI GeneID

3977

NCBI Accession #

NP_002301

UniProt Primary Accession #

P42702

UniProt Secondary Accession #

Q6LCD9

UniProt Related Accession #

P42702

GenBank Nucleotide #

NM_002310.5

NCBI Official Full Name

leukemia inhibitory factor receptor

NCBI Official Synonym Full Names

LIF receptor alpha

NCBI Official Symbol

LIFR

NCBI Official Synonym Symbols

SWS; SJS2; STWS; CD118; LIF-R

UniProt Protein Name

Leukemia inhibitory factor receptor

UniProt Synonym Protein Names

CD_antigen: CD118

Protein Family

Leukemia inhibitory factor receptor

UniProt Gene Name

LIFR

UniProt Synonym Gene Names

LIF receptor; LIF-R

NCBI Protein Information

leukemia inhibitory factor receptor

NCBI Summary for LIFR

This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for LIFR

Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.

Research Articles on LIFR

1. Expression of cancer-specific glycan epitopes represents an excellent opportunity for diagnostics and potentially specific detection of tumors. Here, we report four proteins (LIFR, CE350, VP13A, HPT) found in sera from pancreatic cancer patients carrying aberrant glycan structures as compared to those of controls.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with LIFR recombinant protein

Reference Product	PubMed Publications
LIF recombinant protein	>497 publications with LIFR and LIF
OSM recombinant protein	>406 publications with LIFR and OSM
IL6ST recombinant protein	>127 publications with LIFR and IL6ST
CNTFR recombinant protein	>44 publications with LIFR and CNTFR
JAK1 recombinant protein	>18 publications with LIFR and JAK1
JAK2 recombinant protein	>15 publications with LIFR and JAK2
TYK2 recombinant protein	>8 publications with LIFR and TYK2

Pathways associated with LIFR recombinant protein

Products by Pathway	Pathway Diagram
Adipogenesis Pathway antibodies	Adipogenesis Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
IL-6-type Cytokine Receptor Ligand Interactions Pathway antibodies	IL-6-type Cytokine Receptor Ligand Interactions Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Interleukin-6 Family Signaling Pathway antibodies	Interleukin-6 Family Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Oncostatin M Signaling Pathway antibodies	Oncostatin M Signaling Pathway Diagram

Diseases associated with LIFR recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>43 publications with LIFR and Inflammation
Disease Models, Animal Antibodies	>26 publications with LIFR and Disease Models, Animal
Liver Diseases Antibodies	>23 publications with LIFR and Liver Diseases
Necrosis Antibodies	>22 publications with LIFR and Necrosis
Adenocarcinoma Antibodies	>19 publications with LIFR and Adenocarcinoma
Stuve-Wiedemann syndrome Antibodies	>19 publications with LIFR and Stuve-Wiedemann syndrome
Hypertrophy Antibodies	>17 publications with LIFR and Hypertrophy
Breast Neoplasms Antibodies	>15 publications with LIFR and Breast Neoplasms
Heart Diseases Antibodies	>13 publications with LIFR and Heart Diseases
Liver Neoplasms Antibodies	>13 publications with LIFR and Liver Neoplasms

Organs/Tissues associated with LIFR recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>79 publications with LIFR and Brain
Nerve Antibodies	>73 publications with LIFR and Nerve
Uterus Antibodies	>52 publications with LIFR and Uterus
Embryonic Tissue Antibodies	>46 publications with LIFR and Embryonic Tissue
Muscle Antibodies	>45 publications with LIFR and Muscle
Liver Antibodies	>38 publications with LIFR and Liver
Placenta Antibodies	>29 publications with LIFR and Placenta
Heart Antibodies	>26 publications with LIFR and Heart
Vascular Antibodies	>19 publications with LIFR and Vascular
Lung Antibodies	>13 publications with LIFR and Lung