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DCN Baculovirus Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206205

DCN, also known as decorin isoform, is a small secreted chondroitin/dermatan sulfate proteoglycan within the family of small leucine-rich proteoglycans (SLRPs). This protein has been implicated in matrix assembly and may suppress the growth of various tumor… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DCN, Recombinant Protein
Full Product Name
DCN, 31-359aa, Human, His tag, Baculovirus
Product Gene Name
Product Synonym Names
Decorin isoform; CSCD; DSPG2; PG40; PGII; PGS2; SLRR1B
Sequence
ADPHMDEASG IGPEVPDDRD FEPSLGPVCP FRCQCHLRVV QCSDLGLDKV PKDLPPDTTL LDLQNNKITE IKDGDFKNLK NLHALILVNN KISKVSPGAF TPLVKLERLY LSKNQLKELP EKMPKTLQEL RAHENEITKV RKVTFNGLNQ MIVIELGTNP LKSSGIENGA FQGMKKLSYI RIADTNITSI PQGLPPSLTE LHLDGNKISR VDAASLKGLN NLAKLGLSFN SISAVDNGSL ANTPHLRELH LDNNKLTRVP GGLAEHKYIQ VVYLHNNNIS VVGSSDFCPP GHNTKKASYS GVSLFSNPVQ YWEIQPSTFR CVYVRSAIQL GNYKHHHHHH
Host
Baculovirus
Form/Format
Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol
Purity/Purification
> 95% by SDS-PAGE
Concentration
1mg/ml (determined by Absorbance at 280nm) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
37.1kDa (335aa) 40-57kDa (SDS-PAGE under reducing conditions)
OMIM
M14219 mRNA
3D Structure
ModBase 3D Structure for P07585
Antigen Species
Human
Tag Information
His-tag
Endotoxin Level
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Applications Tested/Suitable for DCN recombinant protein
SDS-PAGE

Product References and Citations for DCN recombinant protein

Mogyorsi A., et al. (1999) Nephrol Dial Transplant. 14 (5):1078-1081.; Reed CC., et al. (2002) Glycoconj J. 19 (4-5):249-255.

Other Notes

Small volumes of DCN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DCN purchase

MBS206205 is a recombinant protein targeting DCN. Also known as DCN, 31-359aa, Human, His tag, Baculovirus. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for DCN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
decorin isoform a preproprotein
NCBI Official Synonym Full Names
decorin
NCBI Official Symbol
DCN
NCBI Official Synonym Symbols
CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B
UniProt Protein Name
Decorin
UniProt Synonym Protein Names
Bone proteoglycan II; PG-S2; PG40
Protein Family
UniProt Gene Name
DCN
UniProt Synonym Gene Names
SLRR1B
NCBI Protein Information
decorin

NCBI Summary for DCN

This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015]
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UniProt Comments for DCN

May affect the rate of fibrils formation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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