Baculovirus CDH5 Recombinant Protein – Cat# MBS206310

Cadherin-5 (CDH5) Baculovirus Recombinant Protein

Name: CDH5 Recombinant Protein; Cadherin-5; Baculovirus; MyBioSource
Brand: MyBioSource
SKU: MBS206310
Price: 265 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206310

CDH5, also known as cadherin-5, is a classical cadherin from the cadherin superfamily and the gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate… More details

$265 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Cadherin-5 (Cdh5), Recombinant Protein

Full Product Name

Cadherin-5, 25-599aa, Mouse, His tag, Baculovirus

Product Gene Name

Cdh5 recombinant protein

Product Synonym Names

Cdh5; 7B4; AA408225; Cd144; VE-Cad; Vec; VEcad; VECD

Sequence

GPNFPQIDTP NMLPAHHRQK RDWIWNQMHI DEEKNESLPH YVGKIKSNVN RQNAKYVLQG EFAGKIFGVD ANTGNVLAYE RLDREKVSEY FLTALIVDKN TNKNLEQPSS FTVKVHDIND NWPVFSHQVF NASVPEMSAI GTSVIRVTAV DADDPTVAGH ATVLYQIVKG NEYFSIDNSG LIFTKIKNLD REKQAEYKIV VETQDALGLR GESGTATVMI RLEDINDNFP VFTQSTYTFS VPEDIRVGKP LGFLTVVDPD EPQNRMTKYS IMQGEYRDTF TIETDPKRNE GIIKPTKSLD YEVIQQYTFY IEATDPTIRY EYLSSTSGKN KAMVTINVLD VDEPPVFQRH FYHFKLPENQ KKPLIGTVVA KDPDKAQRSI GYSIRKTSDR GQFFRITKQG NIYNEKELDR ETYAWYNLTV EANELDSRGN PVGKESIVQV YIEVLDENDN PPEFAQPYEP KVCENAAQGK LVVQISATDK DVVPVNPKFK FALKNEDSNF TLINNHDNTA NITVKYGQFN REHAKFHYLP VLISDNGVPS LTGTSTLTVG VCKCNEQGEF TFCEEMAAQA GVSIQLEHHH HHH

Host

Baculovirus

Form/Format

Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Absorbance at 280nm) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

66.2kDa (583aa) 70-100kDa (SDS-PAGE under reducing conditions)

3D Structure

ModBase 3D Structure for P55284

Antigen Species

Mouse

Tag Information

His-tag

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Product Categories/Family for Cdh5 recombinant protein

Signal Transduction; Cytoskeleton

Applications Tested/Suitable for Cdh5 recombinant protein

SDS-PAGE

Product References and Citations for Cdh5 recombinant protein

Matsuyoshi N., et al. (1997) Proc Assoc Am Physicians. 109:362-371.; Duguay D., et al. (2003) Dev Biol. 253:309-23.

Other Notes

Small volumes of Cdh5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cdh5 purchase

MBS206310 is a recombinant protein targeting Cdh5. Also known as Cadherin-5, 25-599aa, Mouse, His tag, Baculovirus. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for Cdh5. It may not necessarily be applicable to this product.

NCBI GI #

38490561

NCBI GeneID

12562

NCBI Accession #

NP_033998

UniProt Primary Accession #

P55284

UniProt Secondary Accession #

O35542

UniProt Related Accession #

P55284

GenBank Nucleotide #

NM_009868.4

NCBI Official Full Name

cadherin-5 preproprotein

NCBI Official Synonym Full Names

cadherin 5

NCBI Official Symbol

Cdh5

NCBI Official Synonym Symbols

7B4; Vec; VECD; Cd144; VEcad; VE-Cad; AA408225

UniProt Protein Name

Cadherin-5

UniProt Synonym Protein Names

Vascular endothelial cadherin; VE-cadherin; CD_antigen: CD144

Protein Family

Cadherin

UniProt Gene Name

Cdh5

UniProt Synonym Gene Names

VE-cadherin

NCBI Protein Information

cadherin-5

NCBI Summary for Cdh5

This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Mice lacking the encoded protein die in utero due to vascular insufficiency, caused by increased endothelial apoptosis. Multiple distinct genes of the cadherin family, including this gene, are found on chromosome 8. [provided by RefSeq, Oct 2015]

UniProt Comments for Cdh5

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.

Research Articles on Cdh5

1. TM, especially TME45, maintains vascular integrity, at least in part, via Src signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Cdh5 recombinant protein

Reference Product	PubMed Publications
Kdr recombinant protein	>7 publications with Cdh5 and Kdr
Rac1 recombinant protein	>2 publications with Cdh5 and Rac1
Ctnna1 recombinant protein	>1 publications with Cdh5 and Ctnna1
Ctnnb1 recombinant protein	>1 publications with Cdh5 and Ctnnb1

Pathways associated with Cdh5 recombinant protein

Products by Pathway	Pathway Diagram
Adherens Junctions Interactions Pathway antibodies	Adherens Junctions Interactions Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Junction Organization Pathway antibodies	Cell Junction Organization Pathway Diagram
Cell-Cell Communication Pathway antibodies	Cell-Cell Communication Pathway Diagram
Cell-cell Junction Organization Pathway antibodies	Cell-cell Junction Organization Pathway Diagram
Fluid Shear Stress And Atherosclerosis Pathway antibodies	Fluid Shear Stress And Atherosclerosis Pathway Diagram
Fluid Shear Stress And Atherosclerosis Pathway antibodies	Fluid Shear Stress And Atherosclerosis Pathway Diagram
Leukocyte Transendothelial Migration Pathway antibodies	Leukocyte Transendothelial Migration Pathway Diagram
Leukocyte Transendothelial Migration Pathway antibodies	Leukocyte Transendothelial Migration Pathway Diagram

Diseases associated with Cdh5 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>11 publications with Cdh5 and Inflammation
Heart Diseases Antibodies	>10 publications with Cdh5 and Heart Diseases
Lung Diseases Antibodies	>10 publications with Cdh5 and Lung Diseases
Breast Neoplasms Antibodies	>9 publications with Cdh5 and Breast Neoplasms
Fibrosis Antibodies	>6 publications with Cdh5 and Fibrosis
Neoplasm Metastasis Antibodies	>6 publications with Cdh5 and Neoplasm Metastasis
Hypertension Antibodies	>5 publications with Cdh5 and Hypertension
Kidney Diseases Antibodies	>4 publications with Cdh5 and Kidney Diseases
Liver Diseases Antibodies	>4 publications with Cdh5 and Liver Diseases
Neoplasm Invasiveness Antibodies	>3 publications with Cdh5 and Neoplasm Invasiveness

Organs/Tissues associated with Cdh5 recombinant protein

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>21 publications with Cdh5 and Heart
Other Antibodies	>18 publications with Cdh5 and Other
Lung Antibodies	>16 publications with Cdh5 and Lung
Embryonic Tissue Antibodies	>16 publications with Cdh5 and Embryonic Tissue
Brain Antibodies	>8 publications with Cdh5 and Brain
Kidney Antibodies	>7 publications with Cdh5 and Kidney
Eye Antibodies	>4 publications with Cdh5 and Eye
Lymph Node Antibodies	>3 publications with Cdh5 and Lymph Node
Ovary Antibodies	>2 publications with Cdh5 and Ovary
Stomach Antibodies	>2 publications with Cdh5 and Stomach