Baculovirus CD55 Recombinant Protein – Cat# MBS206320

CD55 Baculovirus Recombinant Protein

Name: CD55 Recombinant Protein; Baculovirus; MyBioSource
Brand: MyBioSource
SKU: MBS206320
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206320

CD55, also known as Complement decay-accelerating factor, GPI-anchored, is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It is physiologically… More details

$230 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Cd55, Recombinant Protein

Full Product Name

Cd55, 35-362aa, Mouse, His tag, Baculovirus

Product Gene Name

Cd55 recombinant protein

Product Synonym Names

Complement decay-accelerating factor; GPI-anchored; Daf; Daf-GPI; Daf1; GPI-DAF; Cd55

Sequence

DCGPPPDIPN ARPILGRHSK FAEQSKVAYS CNNGFKQVPD KSNIVVCLEN GQWSSHETFC EKSCVAPERL SFASLKKEYL NMNFFPVGTI VEYECRPGFR KQPPLPGKAT CLEDLVWSPV AQFCKKKSCP NPKDLDNGHI NIPTGILFGS EINFSCNPGY RLVGVSSTFC SVTGNTVDWD DEFPVCTEIH CPEPPKINNG IMRGESDSYT YSQVVTYSCD KGFILVGNAS IYCTVSKSDV GQWSSPPPRC IEKSKVPTKK PTINVPSTGT PSTPQKPTTE SVPNPGDQPT PQKPSTVKVS ATQHVPVTKT TVRHPIRTST DKGEPNTGLE HHHHHH

Host

Baculovirus

Form/Format

Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.

Purity/Purification

> 95% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Absorbance at 280nm) (lot specific)

Preparation and Storage

Can be stored at 4°C short term (1-2 weeks).
For long term storage, aliquot and store at -20°C or -70°C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

36.8kDa (336aa) 40-57kDa (SDS-PAGE under reducing conditions)

3D Structure

ModBase 3D Structure for Q61475

Endotoxin Level

< 1.0 EU per 1 ug of protein (determined by LAL method)

Predicted N terminal

Asp 35

Product Categories/Family for Cd55 recombinant protein

Immunology

Applications Tested/Suitable for Cd55 recombinant protein

SDS-PAGE

Product References and Citations for Cd55 recombinant protein

Lea S., et al. (2002) Biochem Soc Trans. 30:1014-1019.; Wang Y., et al. (2010) J Neuroinflammation. 7:24.

Other Notes

Small volumes of Cd55 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cd55 purchase

MBS206320 is a recombinant protein targeting Cd55. Also known as Cd55, 35-362aa, Mouse, His tag, Baculovirus. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for Cd55. It may not necessarily be applicable to this product.

NCBI GI #

114326522

NCBI GeneID

13136

NCBI Accession #

NP_034146

UniProt Primary Accession #

Q61475

UniProt Secondary Accession #

P97732; Q3TU32; Q4FJS4; Q61397; Q76N72; Q921P0; Q9R1C1

UniProt Related Accession #

Q61475

GenBank Nucleotide #

NM_010016.3

NCBI Official Full Name

complement decay-accelerating factor, GPI-anchored preproprotein

NCBI Official Synonym Full Names

CD55 molecule, decay accelerating factor for complement

NCBI Official Symbol

Cd55

NCBI Official Synonym Symbols

Daf; Daf1; Daf-GPI; GPI-DAF

UniProt Protein Name

Complement decay-accelerating factor, GPI-anchored

UniProt Synonym Protein Names

CD_antigen: CD55

Protein Family

Complement decay-accelerating factor

UniProt Gene Name

Cd55

UniProt Synonym Gene Names

Cd55a; Daf; Daf1; DAF-GPI

NCBI Protein Information

complement decay-accelerating factor, GPI-anchored

NCBI Summary for Cd55

This gene encodes an inhibitor of both the classical and the alternative pathways of complement activation. The encoded preproprotein undergoes post-translational processing to generate a mature polypeptide anchored to the plasma membrane via a glycosylphosphatidylinositol moiety. Erythrocytes from mice deficient in the encoded protein exhibit impaired regulation of complement activation resulting in enhanced complement deposition. Mice lacking the encoded protein exhibit enhanced susceptibility to experimentally induced myasthenia gravis. This gene is located adjacent to a closely related gene on chromosome 1. [provided by RefSeq, Nov 2015]

UniProt Comments for Cd55

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage.

Research Articles on Cd55

1. regulates self-renewal and cisplatin resistance in endometrioid tumors

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Cd55 recombinant protein

Reference Product	PubMed Publications
C4b recombinant protein	>55 publications with Cd55 and C4b
Cd59a recombinant protein	>8 publications with Cd55 and Cd59a
Cfb recombinant protein	>3 publications with Cd55 and Cfb
Cd59b recombinant protein	>1 publications with Cd55 and Cd59b

Pathways associated with Cd55 recombinant protein

Products by Pathway	Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Asparagine N-linked Glycosylation Pathway antibodies	Asparagine N-linked Glycosylation Pathway Diagram
COPI-mediated Anterograde Transport Pathway antibodies	COPI-mediated Anterograde Transport Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
Complement Activation, Classical Pathway antibodies	Complement Activation, Classical Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement Cascade Pathway antibodies	Complement Cascade Pathway Diagram
ER To Golgi Anterograde Transport Pathway antibodies	ER To Golgi Anterograde Transport Pathway Diagram

Diseases associated with Cd55 recombinant protein

Disease Name	Pubmed Publications
Anemia Antibodies	>368 publications with Cd55 and Anemia
Inflammation Antibodies	>164 publications with Cd55 and Inflammation
Necrosis Antibodies	>95 publications with Cd55 and Necrosis
Disease Models, Animal Antibodies	>79 publications with Cd55 and Disease Models, Animal
Kidney Diseases Antibodies	>69 publications with Cd55 and Kidney Diseases
Lung Diseases Antibodies	>38 publications with Cd55 and Lung Diseases
Heart Diseases Antibodies	>27 publications with Cd55 and Heart Diseases
Breast Neoplasms Antibodies	>26 publications with Cd55 and Breast Neoplasms
Liver Diseases Antibodies	>24 publications with Cd55 and Liver Diseases
Brain Diseases Antibodies	>24 publications with Cd55 and Brain Diseases

Organs/Tissues associated with Cd55 recombinant protein

Organ/Tissue Name	Pubmed Publications
Other Antibodies	>412 publications with Cd55 and Other
Bone Marrow Antibodies	>138 publications with Cd55 and Bone Marrow
Muscle Antibodies	>95 publications with Cd55 and Muscle
Lung Antibodies	>93 publications with Cd55 and Lung
Liver Antibodies	>89 publications with Cd55 and Liver
Ovary Antibodies	>51 publications with Cd55 and Ovary
Skin Antibodies	>44 publications with Cd55 and Skin
Intestine Antibodies	>41 publications with Cd55 and Intestine
Spleen Antibodies	>39 publications with Cd55 and Spleen
Embryonic Tissue Antibodies	>38 publications with Cd55 and Embryonic Tissue