Baculovirus TNFRSF18 Recombinant Protein – Cat# MBS206336

TNFRSF18 Baculovirus Recombinant Protein

Name: TNFRSF18 Recombinant Protein; Baculovirus; MyBioSource
Brand: MyBioSource
SKU: MBS206336
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206336

TNFRSF18, also known as tumor necrosis factor receptor superfamily member 18 isoform 1, is receptor for TNFSF18. It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated… More details

$245 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TNFRSF18, Recombinant Protein

Full Product Name

TNFRSF18, 26-162aa, Human, hIgG-His tag, Baculovirus

Product Gene Name

TNFRSF18 recombinant protein

Product Synonym Names

Tumor necrosis factor receptor superfamily member 18 isoform 1; AITR; CD357; GITR; GITR-D

Sequence

QRPTGGPGCG PGRLLLGTGT DARCCRVHTT RCCRDYPGEE CCSEWDCMCV QPEFHCGDPC CTTCRHHPCP PGQGVQSQGK FSFGFQCIDC ASGTFSGGHE GHCKPWTDCT QFGFLTVFPG NKTHNAVCVP GSPPAEPLEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSRDE LTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK HHHHHH

Host

Baculovirus

Form/Format

Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.

Purity/Purification

> 95% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Absorbance at 280nm) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

41.6kDa (376aa) 40-57KDa (SDS-PAGE under reducing conditions.)

OMIM

AF125304 mRNA

3D Structure

ModBase 3D Structure for Q9Y5U5

Antigen Species

Human

Tag Information

hIgG-His-tag

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Product Categories/Family for TNFRSF18 recombinant protein

Hormones & Cytokines; Immunology

Applications Tested/Suitable for TNFRSF18 recombinant protein

SDS-PAGE

Product References and Citations for TNFRSF18 recombinant protein

Lacal PM., et al. (2013) J. Pharmacol. Exp. Ther. 347:164-172.; Xufre C., et al. (2013) Int. Immunol. 25:563-574.; Shimizu J., et al. (2002) Nat. Immunol. 3:135-142.

Other Notes

Small volumes of TNFRSF18 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TNFRSF18 purchase

MBS206336 is a recombinant protein targeting TNFRSF18. Also known as TNFRSF18, 26-162aa, Human, hIgG-His tag, Baculovirus. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for TNFRSF18. It may not necessarily be applicable to this product.

NCBI GI #

4759246

NCBI GeneID

8784

NCBI Accession #

NP_004186

UniProt Primary Accession #

Q9Y5U5

UniProt Secondary Accession #

O95851; Q5U0I4; Q9NYJ9; B1AME1

UniProt Related Accession #

Q9Y5U5

GenBank Nucleotide #

NM_004195.2

NCBI Official Full Name

tumor necrosis factor receptor superfamily member 18 isoform 1

NCBI Official Synonym Full Names

TNF receptor superfamily member 18

NCBI Official Symbol

TNFRSF18

NCBI Official Synonym Symbols

AITR; GITR; CD357; GITR-D

UniProt Protein Name

Tumor necrosis factor receptor superfamily member 18

UniProt Synonym Protein Names

Activation-inducible TNFR family receptor; Glucocorticoid-induced TNFR-related protein; CD_antigen: CD357

Protein Family

Tumor necrosis factor receptor superfamily

UniProt Gene Name

TNFRSF18

UniProt Synonym Gene Names

AITR; GITR

NCBI Protein Information

tumor necrosis factor receptor superfamily member 18

NCBI Summary for TNFRSF18

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]

UniProt Comments for TNFRSF18

Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Research Articles on TNFRSF18

1. HTLV-1 infection can modify the expression of main functional transcription factors, FOXP3 and GITR

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TNFRSF18 recombinant protein

Reference Product	PubMed Publications
FOXP3 recombinant protein	>158 publications with TNFRSF18 and FOXP3
CTLA4 recombinant protein	>72 publications with TNFRSF18 and CTLA4
TNFSF18 recombinant protein	>58 publications with TNFRSF18 and TNFSF18
IL2RA recombinant protein	>22 publications with TNFRSF18 and IL2RA
TNFRSF4 recombinant protein	>19 publications with TNFRSF18 and TNFRSF4
IL2 recombinant protein	>2 publications with TNFRSF18 and IL2
IL2RG recombinant protein	>1 publications with TNFRSF18 and IL2RG

Pathways associated with TNFRSF18 recombinant protein

Products by Pathway	Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Downstream Signaling In Naive CD8+ T Cells Pathway antibodies	Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
TNFR2 Non-canonical NF-kB Pathway antibodies	TNFR2 Non-canonical NF-kB Pathway Diagram
TNFs Bind Their Physiological Receptors Pathway antibodies	TNFs Bind Their Physiological Receptors Pathway Diagram

Diseases associated with TNFRSF18 recombinant protein

Disease Name	Pubmed Publications
Necrosis Antibodies	>282 publications with TNFRSF18 and Necrosis
Immune System Diseases Antibodies	>98 publications with TNFRSF18 and Immune System Diseases
Inflammation Antibodies	>63 publications with TNFRSF18 and Inflammation
Disease Models, Animal Antibodies	>51 publications with TNFRSF18 and Disease Models, Animal
Neoplasms, Experimental Antibodies	>18 publications with TNFRSF18 and Neoplasms, Experimental
Liver Diseases Antibodies	>11 publications with TNFRSF18 and Liver Diseases
Cardiovascular Diseases Antibodies	>10 publications with TNFRSF18 and Cardiovascular Diseases
Vascular Diseases Antibodies	>9 publications with TNFRSF18 and Vascular Diseases
Heart Diseases Antibodies	>5 publications with TNFRSF18 and Heart Diseases
Breast Neoplasms Antibodies	>5 publications with TNFRSF18 and Breast Neoplasms

Organs/Tissues associated with TNFRSF18 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>310 publications with TNFRSF18 and Blood
Lymph Node Antibodies	>34 publications with TNFRSF18 and Lymph Node
Lung Antibodies	>17 publications with TNFRSF18 and Lung
Intestine Antibodies	>9 publications with TNFRSF18 and Intestine
Brain Antibodies	>8 publications with TNFRSF18 and Brain
Kidney Antibodies	>5 publications with TNFRSF18 and Kidney