Baculovirus ACPP Active Protein – Cat# MBS206396

ACPP Baculovirus Active Protein

Name: ACPP Active Protein; Baculovirus; MyBioSource
Brand: MyBioSource
SKU: MBS206396
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206396

ACPP, also known as prostatic acid phosphatase isoform PAP, is a type I integral membrane protein of the plasma membrane and lysosomes, and a secreted form also exists. The concentration of ACPP is elevated in the circulation of prostate cancer patients,… More details

$245 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ACPP, Active Protein

Full Product Name

ACPP, 33-386aa, Human, His-tag, Baculovirus (Bioactivity Validated)

Product Gene Name

ACPP active protein

Product Synonym Names

Prostatic acid phosphatase isoform PAP; ACPP; 5-NT; ACP-3; ACP3; 5-NT; 5-nucleotidase Acid phosphatase prostate; ACP 3; ACP3; acpP Ecto-5-nucleotidase; PAP; PPAP_HUMAN Prostatic acid phosphatase; Thiamine monophosphatase; TMPase

Sequence

KELKFVTLVF RHGDRSPIDT FPTDPIKESS WPQGFGQLTQ LGMEQHYELG EYIRKRYRKF LNESYKHEQV YIRSTDVDRT LMSAMTNLAA LFPPEGVSIW NPILLWQPIP VHTVPLSEDQ LLYLPFRNCP RFQELESETL KSEEFQKRLH PYKDFIATLG KLSGLHGQDL FGIWSKVYDP LYCESVHNFT LPSWATEDTM TKLRELSELS LLSLYGIHKQ KEKSRLQGGV LVNEILNHMK RATQIPSYKK LIMYSAHDTT VSGLQMALDV YNGLLPPYAS CHLTELYFEK GEYFVEMYYR NETQHEPYPL MLPGCSPSCP LERFAELVGP VIPQDWSTEC MTTNSHQGTE DSTDHHHHHH

Host

Baculovirus

Form/Format

Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol

Purity/Purification

> 95% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Absorbance at 280nm) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

41.8kDa (360aa) 40-57KDa (SDS-PAGE under reducing conditions)

3D Structure

ModBase 3D Structure for P15309

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Antigen Species

Human

Tag Information

His-tag

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Biological Activity

Specific activity is > 100,000 units/mg, and is defined as the amount of enzyme that hydrolyze 1.0 nmoles of p-nitrophenyl phosphate (pNPP) per minute at pH 5.0 at 37C.

Product Categories/Family for ACPP active protein

Cancer; Enzymes & Proteases

Applications Tested/Suitable for ACPP active protein

SDS-PAGE

Product References and Citations for ACPP active protein

Chuang TD., et al. (2010) J Biol Chem. 285:23598-23606.; Taira A., et al. (2007) Oncology. 21:1003-1010.;

Other Notes

Small volumes of ACPP active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ACPP purchase

MBS206396 is an active protein targeting ACPP. Also known as ACPP, 33-386aa, Human, His-tag, Baculovirus (Bioactivity Validated). Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for ACPP. It may not necessarily be applicable to this product.

NCBI GI #

6382064

NCBI GeneID

NCBI Accession #

NP_001090

UniProt Primary Accession #

P15309

UniProt Secondary Accession #

Q5FBY0; Q96KY0; Q96QK9; Q96QM0; D3DNC6

UniProt Related Accession #

P15309

GenBank Nucleotide #

NM_001099.4

NCBI Official Full Name

prostatic acid phosphatase isoform PAP

NCBI Official Synonym Full Names

acid phosphatase, prostate

NCBI Official Symbol

ACPP

NCBI Official Synonym Symbols

ACP3; 5'-NT; ACP-3

UniProt Protein Name

Prostatic acid phosphatase

UniProt Synonym Protein Names

5'-nucleotidase (EC:3.1.3.5); 5'-NT

Protein Family

Acyl carrier protein

UniProt Gene Name

ACPP

UniProt Synonym Gene Names

PAP; 5'-NT; TMPase

NCBI Protein Information

prostatic acid phosphatase

NCBI Summary for ACPP

This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]

UniProt Comments for ACPP

A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.

Research Articles on ACPP

1. Enhanced TDPase and TMPase activities may contribute to the reduction of TDP level in AD patients. The results imply that an imbalance of phosphorylation-dephosphorylation related to thiamine and glucose metabolism may be a potential target for AD prevention and therapy.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ACPP active protein

Reference Product	PubMed Publications
KLK3 active protein	>2 publications with ACPP and KLK3
SLC45A3 active protein	>1 publications with ACPP and SLC45A3

Pathways associated with ACPP active protein

Products by Pathway	Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Neutrophil Degranulation Pathway antibodies	Neutrophil Degranulation Pathway Diagram

Diseases associated with ACPP active protein

Disease Name	Pubmed Publications
Prostatic Neoplasms Antibodies	>11 publications with ACPP and Prostatic Neoplasms
Inflammation Antibodies	>7 publications with ACPP and Inflammation
Fibrosis Antibodies	>5 publications with ACPP and Fibrosis
Breast Neoplasms Antibodies	>4 publications with ACPP and Breast Neoplasms
Pain Antibodies	>4 publications with ACPP and Pain
Hyperplasia Antibodies	>4 publications with ACPP and Hyperplasia
Prostatic Hyperplasia Antibodies	>3 publications with ACPP and Prostatic Hyperplasia
Carcinoma, Squamous Cell Antibodies	>3 publications with ACPP and Carcinoma, Squamous Cell
Necrosis Antibodies	>3 publications with ACPP and Necrosis
Neoplasm Metastasis Antibodies	>2 publications with ACPP and Neoplasm Metastasis

Organs/Tissues associated with ACPP active protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>18 publications with ACPP and Blood
Prostate Antibodies	>15 publications with ACPP and Prostate
Brain Antibodies	>14 publications with ACPP and Brain
Muscle Antibodies	>4 publications with ACPP and Muscle
Bone Antibodies	>4 publications with ACPP and Bone
Nerve Antibodies	>2 publications with ACPP and Nerve
Ovary Antibodies	>2 publications with ACPP and Ovary
Skin Antibodies	>2 publications with ACPP and Skin
Connective Tissue Antibodies	>1 publications with ACPP and Connective Tissue
Bone Marrow Antibodies	>1 publications with ACPP and Bone Marrow