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EPHB4 Baculovirus Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206421

Ephb4, also known as ephrin type-B receptor 4 isoform b, is a member of the Eph receptor tyrosine kinase family shown to act in neuronal guidance and mediate venal/arterial separation. Ephb4 provides survival advantage to squamous cell carcinoma of the head… More details

$365 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ephb4, Recombinant Protein
Full Product Name
Ephb4, 16-539aa, Mouse, His tag, Baculovirus
Product Gene Name
Product Synonym Names
Ephrin type-B receptor 4 isoform b; Eph receptor B4; AI042935; Htk; MDK2; Myk1; Tyro11; Ephb4; EPHB4_HUMAN; Ephrin receptor; EphB4; Ephrin type-B receptor 4; Hepatoma Transmembrane Kinase; HTK; MYK 1; MYK1; TYRO 11; TYRO11; Tyrosine-protein kinase receptor HTK; Tyrosine-protein kinase TYRO11
Sequence
LEETLLNTKL ETADLKWVTY PQAEGQWEEL SGLDEEQHSV RTYEVCDMKR PGGQAHWLRT GWVPRRGAVH VYATIRFTMM ECLSLPRASR SCKETFTVFY YESEADTATA HTPAWMENPY IKVDTVAAEH LTRKRPGAEA TGKVNIKTLR LGPLSKAGFY LAFQDQGACM ALLSLHLFYK KCSWLITNLT YFPETVPREL VVPVAGSCVA NAVPTANPSP SLYCREDGQW AEQQVTGCSC APGYEAAESN KVCRACGQGT FKPQIGDESC LPCPANSHSN NIGSPVCLCR IGYYRARSDP RSSPCTTPPS APRSVVHHLN GSTLRLEWSA PLESGGREDL TYAVRCRECR PGGSCLPCGG DMTFDPGPRD LVEPWVAIRG LRPDVTYTFE VAALNGVSTL ATGPPPFEPV NVTTDREVPP AVSDIRVTRS SPSSLILSWA IPRAPSGAVL DYEVKYHEKG AEGPSSVRFL KTSENRAELR GLKRGASYLV QVRARSEAGY GPFGQEHHSQ TQLDESESWR EQLAVEHHHH HH
Host
Baculovirus
Form/Format
Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.
Purity/Purification
> 85% by SDS-PAGE
Concentration
0.25mg/ml (determined by Absorbance at 280nm) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
58.7kDa (532aa) 50-70KDa (SDS-PAGE under reducing conditions)
3D Structure
ModBase 3D Structure for P54761
Antigen Species
Mouse
Tag Information
His-tag
Endotoxin Level
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Applications Tested/Suitable for Ephb4 recombinant protein
SDS-PAGE

Product References and Citations for Ephb4 recombinant protein

Xiao Z. et al., (2012) Cancer Biol Ther. 13:630-637.; Masood R. et al., (2006) Int J Cancer. 119:1236-1248.; Dopeso H. et al., (2009) Cancer Res. 69:7430-7438.

Other Notes

Small volumes of Ephb4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ephb4 purchase

MBS206421 is a recombinant protein targeting Ephb4. Also known as Ephb4, 16-539aa, Mouse, His tag, Baculovirus. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for Ephb4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ephrin type-B receptor 4 isoform b
NCBI Official Synonym Full Names
Eph receptor B4
NCBI Official Symbol
Ephb4
NCBI Official Synonym Symbols
Htk; MDK2; Myk1; Tyro11; AI042935; b2b2412Clo
UniProt Protein Name
Ephrin type-B receptor 4
UniProt Synonym Protein Names
Developmental kinase 2; mDK-2; Hepatoma transmembrane kinase; Tyrosine kinase MYK-1
UniProt Gene Name
Ephb4
UniProt Synonym Gene Names
Htk; Mdk2; Myk1; mDK-2
NCBI Protein Information
ephrin type-B receptor 4

UniProt Comments for Ephb4

Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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