Protease, Serine 12 (PRSS12) ELISA Kit for Human

Name: Human PRSS12 ELISA Kit; Protease, Serine 12; MyBioSource
Brand: MyBioSource
SKU: MBS020644
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS020644

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of PRSS12 (hereafter termed "analyte") in undiluted original Human body fluids, tissue… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Protease, Serine 12 (PRSS12), ELISA Kit

Full Product Name

Human Protease, Serine 12 ELISA Kit

Product Gene Name

PRSS12 elisa kit

Species Reactivity

Human

Assay Type

Sandwich

Samples

Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

Detection Range

0.625ng/ml-20ng/ml.

Sensitivity

0.1ng/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

97,067 Da

Chromosome Location

Chromosome: 4; NC_000004.11 (119201193..119273922, complement). Location: 4q28.1

OMIM

249500

3D Structure

ModBase 3D Structure for P56730

Other Notes

Small volumes of PRSS12 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRSS12 purchase

MBS020644 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Protease, Serine 12 (PRSS12) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PRSS12. The ELISA analytical biochemical technique of the MBS020644 kit is based on PRSS12 antibody-PRSS12 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PRSS12 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PRSS12. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PRSS12. It may not necessarily be applicable to this product.

NCBI GI #

14043559

NCBI GeneID

8492

NCBI Accession #

AAH07761.1

UniProt Primary Accession #

P56730

UniProt Secondary Accession #

Q9UP16

UniProt Related Accession #

P56730

NCBI Official Full Name

PRSS12 protein

NCBI Official Synonym Full Names

protease, serine, 12 (neurotrypsin, motopsin)

NCBI Official Symbol

PRSS12

NCBI Official Synonym Symbols

MRT1; BSSP3; BSSP-3

UniProt Protein Name

Neurotrypsin

UniProt Synonym Protein Names

Leydin; Motopsin; Serine protease 12

Protein Family

Neurotrypsin

UniProt Gene Name

PRSS12

UniProt Entry Name

NETR_HUMAN

NCBI Protein Information

neurotrypsin; leydin; brain-specific serine protease 3

NCBI Summary for PRSS12

This gene encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. Defects in this gene are a cause of mental retardation autosomal recessive type 1 (MRT1). [provided by RefSeq, Jul 2010]

UniProt Comments for PRSS12

PRSS12: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. Defects in PRSS12 are the cause of mental retardation autosomal recessive type 1 (MRT1). Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Belongs to the peptidase S1 family.

Protein type: Secreted; Protease; Secreted, signal peptide; Vesicle; EC 3.4.21.-

Chromosomal Location of Human Ortholog: 4q28.1

Cellular Component: axon; dendrite; plasma membrane; extracellular region; terminal button; cytoplasmic vesicle

Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity; scavenger receptor activity

Biological Process: receptor-mediated endocytosis; exocytosis; zymogen activation; proteolysis

Disease: Mental Retardation, Autosomal Recessive 1

Research Articles on PRSS12

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PRSS12 elisa kit

Reference Product	PubMed Publications
CRBN elisa kit	>2 publications with PRSS12 and CRBN
CC2D1A elisa kit	>2 publications with PRSS12 and CC2D1A

Organs/Tissues associated with PRSS12 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>4 publications with PRSS12 and Brain
Vascular Antibodies	>1 publications with PRSS12 and Vascular
Bone Antibodies	>1 publications with PRSS12 and Bone