Baculovirus RLN2 Recombinant Protein – Cat# MBS206551

RLN2 Baculovirus Recombinant Protein

Name: RLN2 Recombinant Protein; Baculovirus; MyBioSource
Brand: MyBioSource
SKU: MBS206551
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206551

RLN2, as known as prorelaxin H2 isoform 1, belongs to the insulin gene superfamily. This family is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may… More details

$230 / 0.004 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RLN2, Recombinant Protein

Full Product Name

RLN2, 25-185aa, Human, His-tag, Baculovirus

Product Gene Name

RLN2 recombinant protein

Product Synonym Names

Prorelaxin H2 isoform 1; RLN2; bA12D24.1.1; bA12D24.1.2; H2; H2-RLX; RLXH2

Sequence

ADPDSWMEEV IKLCGRELVR AQIAICGMST WSKRSLSQED APQTPRPVAE IVPSFINKDT ETINMMSEFV ANLPQELKLT LSEMQPALPQ LQQHVPVLKD SSLLFEEFKK LIRNRQSEAA DSSPSELKYL GLDTHSRKKR QLYSALANKC CHVGCTKRSL ARFCHHHHHH

Host

Baculovirus

Form/Format

Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.

Purity/Purification

> 85% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Absorbance at 280nm) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

19.3kDa (170aa) 18-28kDa (SDS-PAGE under reducing conditions.)

OMIM

X00948 mRNA

3D Structure

ModBase 3D Structure for P04090

Antigen Species

Human

Tag Information

His-tag

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Product Categories/Family for RLN2 recombinant protein

Signal Transduction; Hormones & Cytokines

Applications Tested/Suitable for RLN2 recombinant protein

SDS-PAGE

Product References and Citations for RLN2 recombinant protein

Ng TM., et al, (2016) Cardiol Rev. 24:194-204.; Sherwood OD., et al, (2004) Endocr. Rev. 25:205-234.

Other Notes

Small volumes of RLN2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RLN2 purchase

MBS206551 is a recombinant protein targeting RLN2. Also known as RLN2, 25-185aa, Human, His-tag, Baculovirus. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for RLN2. It may not necessarily be applicable to this product.

NCBI GI #

20143933

NCBI GeneID

6019

NCBI Accession #

NP_604390

UniProt Primary Accession #

P04090

UniProt Secondary Accession #

Q99936; Q9UCX3; Q9UQJ2; A0AVM0

UniProt Related Accession #

P04090

GenBank Nucleotide #

NM_134441.2

NCBI Official Full Name

prorelaxin H2 isoform 1 preproprotein

NCBI Official Synonym Full Names

relaxin 2

NCBI Official Symbol

RLN2

NCBI Official Synonym Symbols

H2; RLXH2; H2-RLX; bA12D24.1.1; bA12D24.1.2

UniProt Protein Name

Prorelaxin H2

Protein Family

Prorelaxin

UniProt Gene Name

RLN2

NCBI Protein Information

prorelaxin H2

NCBI Summary for RLN2

This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects. [provided by RefSeq, Jul 2016]

UniProt Comments for RLN2

Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.

Research Articles on RLN2

1. In a population of acute HF patients, admission relaxin serum levels were associated with clinical and echocardiographic markers of pulmonary hypertension, RV dysfunction, and overload, suggesting a role for circulating relaxin as a biomarker in this setting.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RLN2 recombinant protein

Reference Product	PubMed Publications
RXFP1 recombinant protein	>35 publications with RLN2 and RXFP1
RXFP2 recombinant protein	>15 publications with RLN2 and RXFP2
INSL3 recombinant protein	>10 publications with RLN2 and INSL3
RLN3 recombinant protein	>10 publications with RLN2 and RLN3
AVP recombinant protein	>1 publications with RLN2 and AVP

Pathways associated with RLN2 recombinant protein

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Relaxin Receptors Pathway antibodies	Relaxin Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with RLN2 recombinant protein

Disease Name	Pubmed Publications
Fibrosis Antibodies	>17 publications with RLN2 and Fibrosis
Disease Models, Animal Antibodies	>9 publications with RLN2 and Disease Models, Animal
Inflammation Antibodies	>9 publications with RLN2 and Inflammation
Prostatic Neoplasms Antibodies	>9 publications with RLN2 and Prostatic Neoplasms
Neoplasm Metastasis Antibodies	>6 publications with RLN2 and Neoplasm Metastasis
Hypertension Antibodies	>5 publications with RLN2 and Hypertension
Lung Diseases Antibodies	>5 publications with RLN2 and Lung Diseases
Breast Neoplasms Antibodies	>4 publications with RLN2 and Breast Neoplasms
Neoplasms, Experimental Antibodies	>2 publications with RLN2 and Neoplasms, Experimental
Lung Neoplasms Antibodies	>2 publications with RLN2 and Lung Neoplasms

Organs/Tissues associated with RLN2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Connective Tissue Antibodies	>6 publications with RLN2 and Connective Tissue
Lung Antibodies	>4 publications with RLN2 and Lung