Baculovirus SIRPG Recombinant Protein – Cat# MBS206578

SIRPG Baculovirus Recombinant Protein

Name: SIRPG Recombinant Protein; Baculovirus; MyBioSource
Brand: MyBioSource
SKU: MBS206578
Price: 445 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206578

SIRPG, also known as signal-regulatory protein gamma isoform 1, is a member of a closely related family of three cell surface receptors implicated in modulating immune/inflammatory responses. It is expressed on T lymphocytes where it appears to be involved in… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

SIRPG, Recombinant Protein

Full Product Name

SIRPG, 29-360aa, Human, hIgG-His-tag, Baculovirus

Product Gene Name

SIRPG recombinant protein

Product Synonym Names

Signal-regulatory protein gamma isoform 1; SIRPG; bA77C3.1; CD172g; SIRP-B2; SIRPB2; SIRPgamma

Sequence

ADPEEELQMI QPEKLLLVTV GKTATLHCTV TSLLPVGPVL WFRGVGPGRE LIYNQKEGHF PRVTTVSDLT KRNNMDFSIR ISSITPADVG TYYCVKFRKG SPENVEFKSG PGTEMALGAK PSAPVVLGPA ARTTPEHTVS FTCESHGFSP RDITLKWFKN GNELSDFQTN VDPTGQSVAY SIRSTARVVL DPWDVRSQVI CEVAHVTLQG DPLRGTANLS EAIRVPPTLE VTQQPMRVGN QVNVTCQVRK FYPQSLQLTW SENGNVCQRE TASTLTENKD GTYNWTSWFL VNISDQRDDV VLTCQVKHDG QLAVSKRLAL EVTVHQKDQS SDATPLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH

Host

Baculovirus

Form/Format

Liquid. In phosphate buffered saline (pH 7.4) containing 20% glycerol.

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Absorbance at 280nm) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

64.0kDa (574aa) 70-100kDa (SDS-PAGE under reducing conditions)

OMIM

AB042624 mRNA

3D Structure

ModBase 3D Structure for Q9P1W8

Antigen Species

Human

Tag Information

hIgG-His-tag

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Product Categories/Family for SIRPG recombinant protein

Immunology; Adhesion & Movement

Applications Tested/Suitable for SIRPG recombinant protein

SDS-PAGE

Product References and Citations for SIRPG recombinant protein

Nettleship JE., et al. (2013) BMC Struct Biol. 13:13.; Brooke G., et al. (2004) J Immunol. 173:2562-2570

Other Notes

Small volumes of SIRPG recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SIRPG purchase

MBS206578 is a recombinant protein targeting SIRPG. Also known as SIRPG, 29-360aa, Human, hIgG-His-tag, Baculovirus. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for SIRPG. It may not necessarily be applicable to this product.

NCBI GI #

94538335

NCBI GeneID

55423

NCBI Accession #

NP_061026

UniProt Primary Accession #

Q9P1W8

UniProt Secondary Accession #

Q5D051; Q5JV25; Q5MKL4; Q8WWA5; Q9NQK8; B1AKP6

UniProt Related Accession #

Q9P1W8

GenBank Nucleotide #

NM_018556.3

NCBI Official Full Name

signal-regulatory protein gamma isoform 1

NCBI Official Synonym Full Names

signal regulatory protein gamma

NCBI Official Symbol

SIRPG

NCBI Official Synonym Symbols

CD172g; SIRPB2; SIRP-B2; bA77C3.1; SIRPgamma

UniProt Protein Name

Signal-regulatory protein gamma

UniProt Synonym Protein Names

CD172 antigen-like family member B; Signal-regulatory protein beta-2; SIRP-b2; SIRP-beta-2; CD_antigen: CD172g

Protein Family

Signal-regulatory protein

UniProt Gene Name

SIRPG

UniProt Synonym Gene Names

SIRPB2; SIRP-gamma; SIRP-b2; SIRP-beta-2

NCBI Protein Information

signal-regulatory protein gamma

NCBI Summary for SIRPG

The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

UniProt Comments for SIRPG

Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.

Research Articles on SIRPG

1. SIRPgamma in complex with FabOX117 forms a dimer in the crystal. Binding to the Fab fixes the position of domain 1 relative to domains 2/3 exposing a surface which favours formation of a homotypic dimer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SIRPG recombinant protein

Reference Product	PubMed Publications
CD47 recombinant protein	>4 publications with SIRPG and CD47
TYROBP recombinant protein	>1 publications with SIRPG and TYROBP

Pathways associated with SIRPG recombinant protein

Products by Pathway	Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
Cell-Cell Communication Pathway antibodies	Cell-Cell Communication Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram
Signal Regulatory Protein (SIRP) Family Interactions Pathway antibodies	Signal Regulatory Protein (SIRP) Family Interactions Pathway Diagram

Diseases associated with SIRPG recombinant protein

Disease Name	Pubmed Publications
Male Urogenital Diseases Antibodies	>2 publications with SIRPG and Male Urogenital Diseases
Inflammation Antibodies	>2 publications with SIRPG and Inflammation
Chromosome Disorders Antibodies	>1 publications with SIRPG and Chromosome Disorders
Oligospermia Antibodies	>1 publications with SIRPG and Oligospermia
Chromosome Aberrations Antibodies	>1 publications with SIRPG and Chromosome Aberrations
Necrosis Antibodies	>1 publications with SIRPG and Necrosis
Chromosome Breakage Antibodies	>1 publications with SIRPG and Chromosome Breakage

Organs/Tissues associated with SIRPG recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with SIRPG and Blood
Thymus Antibodies	>1 publications with SIRPG and Thymus