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Vascular Endothelial Growth Inhibitor (VEGI) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2067041
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MBS2067041 is an antibody targeting VEGI. Also known as FITC-Linked Polyclonal Antibody to Vascular Endothelial Growth Inhibitor (VEGI). Reactive in Rat. Host: Rabbit. More details

$280 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Vascular Endothelial Growth Inhibitor (VEGI), Polyclonal Antibody
Full Product Name
FITC-Linked Polyclonal Antibody to Vascular Endothelial Growth Inhibitor (VEGI)
Product Gene Name
Product Synonym Names
TNFSF15; TL1; TL1A; VEGI192A; Tumor Necrosis Factor (ligand)Superfamily, Member 15; TNF Superfamily Ligand TL1A; TNF Ligand-Related Molecule 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: VEGI (MBS2026745)
FITC Conjugated Antibody: VEGI (MBS2067041)
Matching Pairs
FITC Conjugated Antibody: VEGI (MBS2067041)
Immunogen: VEGI (MBS2030692)
Molecular Weight
20,131 Da
OMIM
AF039390 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
VEGI (Asp70~Asn230)
Conjugation
FITC
Cross Reactivity
Rat
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2026745
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-VEGI antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-VEGI antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for VEGI. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
vascular endothelial cell growth inhibitor
NCBI Official Synonym Full Names
tumor necrosis factor superfamily member 15
NCBI Official Symbol
TNFSF15
NCBI Official Synonym Symbols
TL1; TL1A; VEGI; TNLG1B; VEGI192A
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 15
UniProt Synonym Protein Names
TNF ligand-related molecule 1; Vascular endothelial cell growth inhibitor
UniProt Gene Name
TNFSF15
UniProt Synonym Gene Names
TL1; VEGI
NCBI Protein Information
tumor necrosis factor ligand superfamily member 15

NCBI Summary for VEGI

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
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UniProt Comments for VEGI

TNFSF15: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. Belongs to the tumor necrosis factor family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q32

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: receptor binding

Biological Process: activation of NF-kappaB-inducing kinase; caspase activation; cytokine metabolic process; tumor necrosis factor-mediated signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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