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MAP1LC3B Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206718

Map1lc3b, also known as Microtubule-associated proteins 1A/1B light chain 3B, belongs to the MAP1 LC3 family. It is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for… More details

$230 / 0.02 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Map1lc3b, Recombinant Protein
Full Product Name
Map1lc3b, 1-120aa, Mouse, His-tag, E Coli
Product Synonym Names
Microtubule-associated proteins 1A/1B light chain 3B; 1010001C15Rik; Atg8; LC3b; Map1lc3
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMPSEKT FKQRRSFEQR VEDVRLIREQ HPTKIPVIIE RYKGEKQLPV LDKTKFLVPD HVNMSELIKI IRRRLQLNAN QAFFLLVNGH SMVSVSTPIS EVYESERDED GFLYMVYASQ ETFG
Host
E Coli
Form/Format
Liquid. In 20mM MES (pH 6.0) containing 0.1M NaCl, 1mM DTT, 30% glycerol
Purity/Purification
> 95% by SDS-PAGE
Concentration
0.25 mg/ml (determined by Absorbance at 280nm) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
16.7 kDa (144aa) Confirmed by MALDI-TOF
3D Structure
ModBase 3D Structure for Q9CQV6
Antigen Species
Human
Tag Information
His-tag
Applications Tested/Suitable for Map1lc3b recombinant protein
SDS-PAGE

Product References and Citations for Map1lc3b recombinant protein

Behrends C., et al. (2010) Nature. 466 (7302):68-76.; Yu S., et al. (2016) Tumour Biol. 37 (11):15007-15017

Other Notes

Small volumes of Map1lc3b recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Map1lc3b purchase

MBS206718 is a recombinant protein targeting Map1lc3b. Also known as Map1lc3b, 1-120aa, Mouse, His-tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Map1lc3b. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
microtubule-associated proteins 1A/1B light chain 3B
NCBI Official Synonym Full Names
microtubule-associated protein 1 light chain 3 beta
NCBI Official Symbol
Map1lc3b
NCBI Official Synonym Symbols
Atg8; LC3b; Map1lc3; 1010001C15Rik
UniProt Protein Name
Microtubule-associated proteins 1A/1B light chain 3B
UniProt Synonym Protein Names
Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B light chain 3 B; MAP1A/MAP1B LC3 B; Microtubule-associated protein 1 light chain 3 beta
UniProt Gene Name
Map1lc3b
UniProt Synonym Gene Names
Map1alc3; Map1lc3; MAP1A/MAP1B LC3 B
NCBI Protein Information
microtubule-associated proteins 1A/1B light chain 3B

UniProt Comments for Map1lc3b

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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