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HSPA5 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206735

HSPA5, also known as 78 kDa glucose-regulated protein precursor, is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As… More details

$365 / 0.01 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Hspa5, Recombinant Protein
Full Product Name
Hspa5, 20-655aa, Mouse, His-tag, E Coli
Product Gene Name
Product Synonym Names
78 kDa glucose-regulated protein precursor; AL022860; AU019543; baffled; Bip; D2Wsu141e; D2Wsu17e; Grp78; Hsce70; mBiP; SEZ-7; Sez7
Sequence
MGSSHHHHHH SSGLVPRGSH MGSEEEDKKE DVGTVVGIDL GTTYSCVGVF KNGRVEIIAN DQGNRITPSY VAFTPEGERL IGDAAKNQLT SNPENTVFDA KRLIGRTWND PSVQQDIKFL PFKVVEKKTK PYIQVDIGGG QTKTFAPEEI SAMVLTKMKE TAEAYLGKKV THAVVTVPAY FNDAQRQATK DAGTIAGLNV MRIINEPTAA AIAYGLDKRE GEKNILVFDL GGGTFDVSLL TIDNGVFEVV ATNGDTHLGG EDFDQRVMEH FIKLYKKKTG KDVRKDNRAV QKLRREVEKA KRALSSQHQA RIEIESFFEG EDFSETLTRA KFEELNMDLF RSTMKPVQKV LEDSDLKKSD IDEIVLVGGS TRIPKIQQLV KEFFNGKEPS RGINPDEAVA YGAAVQAGVL SGDQDTGDLV LLDVCPLTLG IETVGGVMTK LIPRNTVVPT KKSQIFSTAS DNQPTVTIKV YEGERPLTKD NHLLGTFDLT GIPPAPRGVP QIEVTFEIDV NGILRVTAED KGTGNKNKIT ITNDQNRLTP EEIERMVNDA EKFAEEDKKL KERIDTRNEL ESYAYSLKNQ IGDKEKLGGK LSSEDKETME KAVEEKIEWL ESHQDADIED FKAKKKELEE IVQPIISKLY GSGGPPPTGE EDTSEKDEL
Host
E Coli
Form/Format
Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol
Purity/Purification
> 90% by SDS-PAGE
Concentration
0.5 mg/ml (determined by Absorbance at 280nm) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
72.9 kDa (659aa) Confirmed by MALDI-TOF
3D Structure
ModBase 3D Structure for P20029
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for Hspa5 recombinant protein

Applications Tested/Suitable for Hspa5 recombinant protein
SDS-PAGE

Product References and Citations for Hspa5 recombinant protein

Wang Q., et al. (2012). Int J Oncol. 41 (2):652-60.; Sokolowska I., et al. (2012). FEBS J. 279 (14):2579-94.

Other Notes

Small volumes of Hspa5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Hspa5 purchase

MBS206735 is a recombinant protein targeting Hspa5. Also known as Hspa5, 20-655aa, Mouse, His-tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Hspa5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
78 kDa glucose-regulated protein
NCBI Official Synonym Full Names
heat shock protein 5
NCBI Official Symbol
Hspa5
NCBI Official Synonym Symbols
Bip; Sez7; mBiP; Grp78; SEZ-7; Hsce70; baffled; AL022860; AU019543; D2Wsu17e; D2Wsu141e
UniProt Protein Name
78 kDa glucose-regulated protein
UniProt Synonym Protein Names
Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein
Protein Family
UniProt Gene Name
Hspa5
UniProt Synonym Gene Names
BiP
NCBI Protein Information
78 kDa glucose-regulated protein

UniProt Comments for Hspa5

Plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum (PubMed:12475965). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate (PubMed:12411443).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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