Baculovirus CD33 Recombinant Protein – Cat# MBS206737

CD33 Baculovirus Recombinant Protein

Name: CD33 Recombinant Protein; Baculovirus; MyBioSource
Brand: MyBioSource
SKU: MBS206737
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206737

CD33, also known as myeloid cell surface antigen CD33 isoform 1, is a member of the Ig superfamily that is restricted to cells of the myelomonocytic lineage but whose functions and binding properties are unknown. It can function as a sialic acid-dependent… More details

$245 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD33, Recombinant Protein

Full Product Name

CD33, 18-259aa, Human, hIgG-His-tag, Baculovirus

Product Gene Name

CD33 recombinant protein

Product Synonym Names

Myeloid cell surface antigen CD33 isoform 1; CD33; FLJ00391; p67; SIGLEC-3; SIGLEC3

Sequence

ADLDPNFWLQ VQESVTVQEG LCVLVPCTFF HPIPYYDKNS PVHGYWFREG AIISGDSPVA TNKLDQEVQE ETQGRFRLLG DPSRNNCSLS IVDARRRDNG SYFFRMERGS TKYSYKSPQL SVHVTDLTHR PKILIPGTLE PGHSKNLTCS VSWACEQGTP PIFSWLSAAP TSLGPRTTHS SVLIITPRPQ DHGTNLTCQV KFAGAGVTTE RTIQLNVTYV PQNPTTGIFP GDGSGKQETR AGVVHLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH

Host

Baculovirus

Form/Format

Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.25mg/ml (determined by Absorbance at 280nm) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

54kDa (484aa) 50-70kDa (SDS-PAGE under reducing conditions)

OMIM

M23197 mRNA

3D Structure

ModBase 3D Structure for P20138

Antigen Species

Human

Tag Information

hIgG-His-tag

Endotoxin Level

< 1.0 EU per 1ug of protein (determined by LAL method)

Product Categories/Family for CD33 recombinant protein

Immunology

Applications Tested/Suitable for CD33 recombinant protein

SDS-PAGE

Product References and Citations for CD33 recombinant protein

Freeman SD., et al. (1995) Blood. 85:2005-2012.; Ulyanova T., et al. (1999) Eur J Immunol. 29:3440-3449.

Other Notes

Small volumes of CD33 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD33 purchase

MBS206737 is a recombinant protein targeting CD33. Also known as CD33, 18-259aa, Human, hIgG-His-tag, Baculovirus. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for CD33. It may not necessarily be applicable to this product.

NCBI GI #

130979981

NCBI GeneID

945

NCBI Accession #

NP_001763

UniProt Primary Accession #

P20138

UniProt Secondary Accession #

Q8TD24; B4E3P8; C9JEN7; F8WAL2

UniProt Related Accession #

P20138

GenBank Nucleotide #

NM_001772.3

NCBI Official Full Name

myeloid cell surface antigen CD33 isoform 1

NCBI Official Synonym Full Names

CD33 molecule

NCBI Official Symbol

CD33

NCBI Official Synonym Symbols

p67; SIGLEC3; SIGLEC-3

UniProt Protein Name

Myeloid cell surface antigen CD33

UniProt Synonym Protein Names

Sialic acid-binding Ig-like lectin 3; Siglec-3; gp67; CD_antigen: CD33

Protein Family

Myeloid cell surface antigen

UniProt Gene Name

CD33

UniProt Synonym Gene Names

SIGLEC3; Siglec-3

NCBI Protein Information

myeloid cell surface antigen CD33

UniProt Comments for CD33

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Research Articles on CD33

1. The mean percentage of CD33-positivity of the myeloblast population was 80.5% in acute myeloid leukemia (AML), 81.8% in chronic myelomonocytic leukemia (CMML) and 75% in myelodysplastic syndromes (MDS).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CD33 recombinant protein

Reference Product	PubMed Publications
CD34 recombinant protein	>1159 publications with CD33 and CD34
CD19 recombinant protein	>508 publications with CD33 and CD19
CD7 recombinant protein	>405 publications with CD33 and CD7
CD38 recombinant protein	>338 publications with CD33 and CD38
CD2 recombinant protein	>248 publications with CD33 and CD2
ITGAM recombinant protein	>10 publications with CD33 and ITGAM
FUT4 recombinant protein	>2 publications with CD33 and FUT4
NCAM1 recombinant protein	>2 publications with CD33 and NCAM1
ANPEP recombinant protein	>1 publications with CD33 and ANPEP

Pathways associated with CD33 recombinant protein

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies	Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Neutrophil Degranulation Pathway antibodies	Neutrophil Degranulation Pathway Diagram

Diseases associated with CD33 recombinant protein

Disease Name	Pubmed Publications
Leukemia, Myeloid, Acute Antibodies	>1304 publications with CD33 and Leukemia, Myeloid, Acute
Death Antibodies	>108 publications with CD33 and Death
Inflammation Antibodies	>107 publications with CD33 and Inflammation
Cell Transformation, Neoplastic Antibodies	>102 publications with CD33 and Cell Transformation, Neoplastic
Necrosis Antibodies	>98 publications with CD33 and Necrosis
Cardiovascular Diseases Antibodies	>90 publications with CD33 and Cardiovascular Diseases
Alzheimer Disease Antibodies	>68 publications with CD33 and Alzheimer Disease
Respiratory Tract Diseases Antibodies	>61 publications with CD33 and Respiratory Tract Diseases
Breast Neoplasms Antibodies	>51 publications with CD33 and Breast Neoplasms
Lung Diseases Antibodies	>46 publications with CD33 and Lung Diseases

Organs/Tissues associated with CD33 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1603 publications with CD33 and Blood
Bone Antibodies	>1093 publications with CD33 and Bone
Bone Marrow Antibodies	>1076 publications with CD33 and Bone Marrow
Liver Antibodies	>105 publications with CD33 and Liver
Lymph Node Antibodies	>76 publications with CD33 and Lymph Node
Lung Antibodies	>64 publications with CD33 and Lung
Brain Antibodies	>58 publications with CD33 and Brain
Thymus Antibodies	>30 publications with CD33 and Thymus
Kidney Antibodies	>25 publications with CD33 and Kidney
Connective Tissue Antibodies	>17 publications with CD33 and Connective Tissue