Baculovirus FCER2 Recombinant Protein – Cat# MBS206755

FCER2 Baculovirus Recombinant Protein

Name: FCER2 Recombinant Protein; Baculovirus; MyBioSource
Brand: MyBioSource
SKU: MBS206755
Price: 265 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206755

FCER2, also known as low affinity immunoglobulin epsilon Fc receptor isoform a, is a member of subgroup II of the C-type (Ca++-dependent) lectin superfamily. It is a low affinity receptor for B cell specific antigen and IgE. It plays an essential role in the… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

FCER2, Recombinant Protein

Full Product Name

FCER2, 48-321aa, Human, His-tag, Baculovirus

Product Gene Name

FCER2 recombinant protein

Product Synonym Names

Low affinity immunoglobulin epsilon Fc receptor isoform a; FECR2; BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF

Sequence

ADPDTTQSLK QLEERAARNV SQVSKNLESH HGDQMAQKSQ STQISQELEE LRAEQQRLKS QDLELSWNLN GLQADLSSFK SQELNERNEA SDLLERLREE VTKLRMELQV SSGFVCNTCP EKWINFQRKC YYFGKGTKQW VHARYACDDM EGQLVSIHSP EEQDFLTKHA SHTGSWIGLR NLDLKGEFIW VDGSHVDYSN WAPGEPTSRS QGEDCVMMRG SGRWNDAFCD RKLGAWVCDR LATCTPPASE GSAESMGPDS RPDPDGRLPT PSAPLHSHHH HHH

Host

Baculovirus

Form/Format

Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.25mg/ml (determined by Absorbance at 280nm) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

32.0kDa (283aa) 28-40kDa (SDS-PAGE under reducing conditions)

OMIM

M15059 mRNA

3D Structure

ModBase 3D Structure for P06734

Antigen Species

Human

Tag Information

His-tag

Endotoxin Level

< 1.0 EU per 1ug of protein (determined by LAL method)

Product Categories/Family for FCER2 recombinant protein

Immunology

Applications Tested/Suitable for FCER2 recombinant protein

SDS-PAGE

Product References and Citations for FCER2 recombinant protein

Heyman, B., et al. (2000) Annu. Rev. Immunol. 18:709-737.; Bajorath, J., et al. (1996) Protein Sci. 5:240-247.

Other Notes

Small volumes of FCER2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FCER2 purchase

MBS206755 is a recombinant protein targeting FCER2. Also known as FCER2, 48-321aa, Human, His-tag, Baculovirus. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for FCER2. It may not necessarily be applicable to this product.

NCBI GI #

20149533

NCBI GeneID

2208

NCBI Accession #

NP_001993

UniProt Primary Accession #

P06734

UniProt Related Accession #

P06734

GenBank Nucleotide #

NM_002002.4

NCBI Official Full Name

low affinity immunoglobulin epsilon Fc receptor isoform a

NCBI Official Synonym Full Names

Fc fragment of IgE receptor II

NCBI Official Symbol

FCER2

NCBI Official Synonym Symbols

CD23; FCE2; CD23A; IGEBF; CLEC4J; BLAST-2

UniProt Protein Name

Low affinity immunoglobulin epsilon Fc receptor

UniProt Synonym Protein Names

BLAST-2; C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor; CD_antigen: CD23

Protein Family

Low affinity immunoglobulin epsilon Fc receptor

UniProt Gene Name

FCER2

UniProt Synonym Gene Names

CD23A; CLEC4J; FCE2; IGEBF

NCBI Protein Information

low affinity immunoglobulin epsilon Fc receptor

NCBI Summary for FCER2

The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

UniProt Comments for FCER2

Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).

Research Articles on FCER2

1. Report a variant of t(14;18) negative nodal diffuse follicular lymphoma with CD23 expression, 1p36/TNFRSF14 abnormalities, and STAT6 mutations.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FCER2 recombinant protein

Reference Product	PubMed Publications
NOTCH2 recombinant protein	>1 publications with FCER2 and NOTCH2

Pathways associated with FCER2 recombinant protein

Products by Pathway	Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
IL4-mediated Signaling Events Pathway antibodies	IL4-mediated Signaling Events Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Interleukin-10 Signaling Pathway antibodies	Interleukin-10 Signaling Pathway Diagram
Interleukin-4 And 13 Signaling Pathway antibodies	Interleukin-4 And 13 Signaling Pathway Diagram
NOTCH2 Intracellular Domain Regulates Transcription Pathway antibodies	NOTCH2 Intracellular Domain Regulates Transcription Pathway Diagram

Diseases associated with FCER2 recombinant protein

Disease Name	Pubmed Publications
Asthma Antibodies	>20 publications with FCER2 and Asthma
Lung Diseases Antibodies	>18 publications with FCER2 and Lung Diseases
Hypersensitivity Antibodies	>17 publications with FCER2 and Hypersensitivity
Hypersensitivity, Immediate Antibodies	>17 publications with FCER2 and Hypersensitivity, Immediate
Inflammation Antibodies	>5 publications with FCER2 and Inflammation
Lung Neoplasms Antibodies	>1 publications with FCER2 and Lung Neoplasms
Carcinoma Antibodies	>1 publications with FCER2 and Carcinoma
Hyperplasia Antibodies	>1 publications with FCER2 and Hyperplasia
Bronchial Hyperreactivity Antibodies	>1 publications with FCER2 and Bronchial Hyperreactivity

Organs/Tissues associated with FCER2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>15 publications with FCER2 and Blood
Lymph Node Antibodies	>2 publications with FCER2 and Lymph Node
Spleen Antibodies	>2 publications with FCER2 and Spleen
Vascular Antibodies	>1 publications with FCER2 and Vascular