Baculovirus MBL2 Recombinant Protein – Cat# MBS206798

MBL2 Baculovirus Recombinant Protein

Name: MBL2 Recombinant Protein; Baculovirus; MyBioSource
Brand: MyBioSource
SKU: MBS206798
Price: 275 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206798

MBL2, also known as mannose-binding protein C, belongs to the class of collectins in the C-type lectin superfamily. It is a lectin that is instrumental in innate immunity via the lectin pathway. It recognizes carbohydrate patterns, found on the surface of a… More details

$275 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MBL2, Recombinant Protein

Full Product Name

MBL2, 21-248aa, Human, His-tag, Baculovirus

Product Gene Name

MBL2 recombinant protein

Product Synonym Names

Mannose-binding protein C; MBL2; COLEC1; HSMBPC; MBL; MBL2D; MBP; MBP-C; MBP1; MBPD

Sequence

ADPETVTCED AQKTCPAVIA CSSPGINGFP GKDGRDGTKG EKGEPGQGLR GLQGPPGKLG PPGNPGPSGS PGPKGQKGDP GKSPDGDSSL AASERKALQT EMARIKKWLT FSLGKQVGNK FFLTNGEIMT FEKVKALCVK FQASVATPRN AAENGAIQNL IKEEAFLGIT DEKTEGQFVD LTGNRLTYTN WNEGEPNNAG SDEDCVLLLK NGQWNDVPCS TSHLAVCEFP IHHHHHH

Host

Baculovirus

Form/Format

Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.

Purity/Purification

> 90% by SDS-PAGE

Concentration

1mg/ml (determined by Absorbance at 280nm) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

25.1kDa (237aa) 28-40kDa (SDS-PAGE under reducing conditions)

OMIM

X15422 mRNA

3D Structure

ModBase 3D Structure for P11226

Antigen Species

Human

Tag Information

His-tag

Endotoxin Level

< 1.0 EU per 1ug of protein (determined by LAL method)

Product Categories/Family for MBL2 recombinant protein

Immunology

Applications Tested/Suitable for MBL2 recombinant protein

SDS-PAGE

Product References and Citations for MBL2 recombinant protein

Tomaiuolo R., et al. (2012) Aging Cell. 11:394-400.; Stuart LM., et al. (2005) J Immunol. 174:3220-3226.

Other Notes

Small volumes of MBL2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MBL2 purchase

MBS206798 is a recombinant protein targeting MBL2. Also known as MBL2, 21-248aa, Human, His-tag, Baculovirus. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for MBL2. It may not necessarily be applicable to this product.

NCBI GI #

4557739

NCBI GeneID

4153

NCBI Accession #

NP_000233

UniProt Primary Accession #

P11226

UniProt Secondary Accession #

Q4VB12; Q4VB13; Q4VB14; Q5SQS3; Q86SI4; Q96KE4; Q96TF7; Q96TF8; Q96TF9

UniProt Related Accession #

P11226

GenBank Nucleotide #

NM_000242.2

NCBI Official Full Name

mannose-binding protein C

NCBI Official Synonym Full Names

mannose binding lectin 2

NCBI Official Symbol

MBL2

NCBI Official Synonym Symbols

MBL; MBP; MBP1; MBPD; MBL2D; MBP-C; COLEC1; HSMBPC

UniProt Protein Name

Mannose-binding protein C

UniProt Synonym Protein Names

Collectin-1; MBP1; Mannan-binding protein; Mannose-binding lectin

Protein Family

Mannose-binding protein

UniProt Gene Name

MBL2

UniProt Synonym Gene Names

COLEC1; MBL; MBP-C

NCBI Protein Information

mannose-binding protein C

NCBI Summary for MBL2

This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008]

UniProt Comments for MBL2

Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.

Research Articles on MBL2

1. These results indicated that polymorphisms in MBL2 gene may influence susceptibility, progression and prognosis of HBV-related liver diseases.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MBL2 recombinant protein

Reference Product	PubMed Publications
MASP2 recombinant protein	>43 publications with MBL2 and MASP2
FCN2 recombinant protein	>25 publications with MBL2 and FCN2
MASP1 recombinant protein	>9 publications with MBL2 and MASP1
FCN3 recombinant protein	>6 publications with MBL2 and FCN3
SERPING1 recombinant protein	>5 publications with MBL2 and SERPING1
C4B recombinant protein	>5 publications with MBL2 and C4B
FCN1 recombinant protein	>4 publications with MBL2 and FCN1
C4A recombinant protein	>2 publications with MBL2 and C4A

Pathways associated with MBL2 recombinant protein

Products by Pathway	Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement Cascade Pathway antibodies	Complement Cascade Pathway Diagram
Creation Of C4 And C2 Activators Pathway antibodies	Creation Of C4 And C2 Activators Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Initial Triggering Of Complement Pathway antibodies	Initial Triggering Of Complement Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Lectin Pathway Of Complement Activation antibodies	Lectin Pathway Of Complement Activation Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram

Diseases associated with MBL2 recombinant protein

Disease Name	Pubmed Publications
Infection Antibodies	>260 publications with MBL2 and Infection
Inflammation Antibodies	>104 publications with MBL2 and Inflammation
Liver Diseases Antibodies	>47 publications with MBL2 and Liver Diseases
HIV Infections Antibodies	>32 publications with MBL2 and HIV Infections
Hepatitis Antibodies	>31 publications with MBL2 and Hepatitis
Fibrosis Antibodies	>31 publications with MBL2 and Fibrosis
Heart Diseases Antibodies	>25 publications with MBL2 and Heart Diseases
Necrosis Antibodies	>24 publications with MBL2 and Necrosis
Disease Models, Animal Antibodies	>21 publications with MBL2 and Disease Models, Animal
Kidney Diseases Antibodies	>17 publications with MBL2 and Kidney Diseases

Organs/Tissues associated with MBL2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>65 publications with MBL2 and Liver
Mixed Antibodies	>5 publications with MBL2 and Mixed