Baculovirus PCOLCE Recombinant Protein – Cat# MBS206814

PCOLCE Baculovirus Recombinant Protein

Name: PCOLCE Recombinant Protein; Baculovirus; MyBioSource
Brand: MyBioSource
SKU: MBS206814
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206814

PCOLCE, also known as procollagen C-endopeptidase enhancer 1, is a secreted extracellular matrix glycoprotein. This protein is expressed primarily by interstitial connective tissues such as tendons, calvaria, and skin. Also, fibrillar collagen types I-III are… More details

$230 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PCOLCE, Recombinant Protein

Full Product Name

PCOLCE, 26-449aa, Human, His-tag, Baculovirus

Product Gene Name

PCOLCE recombinant protein

Product Synonym Names

Procollagen C-endopeptidase enhancer 1; PCOLCE PCPE; PCPE-1; PCPE1

Sequence

ADPQTPNYTR PVFLCGGDVK GESGYVASEG FPNLYPPNKE CIWTITVPEG QTVSLSFRVF DLELHPACRY DALEVFAGSG TSGQRLGRFC GTFRPAPLVA PGNQVTLRMT TDEGTGGRGF LLWYSGRATS GTEHQFCGGR LEKAQGTLTT PNWPESDYPP GISCSWHIIA PPDQVIALTF EKFDLEPDTY CRYDSVSVFN GAVSDDSRRL GKFCGDAVPG SISSEGNELL VQFVSDLSVT ADGFSASYKT LPRGTAKEGQ GPGPKRGTEP KVKLPPKSQP PEKTEESPSA PDAPTCPKQC RRTGTLQSNF CASSLVVTAT VKSMVREPGE GLAVTVSLIG AYKTGGLDLP SPPTGASLKF YVPCKQCPPM KKGVSYLLMG QVEENRGPVL PPESFVVLHR PNQDQILTNL SKRKCPSQPV RAAASQDHHH HHH

Host

Baculovirus

Form/Format

Liquid. In 20mM Tris-HCl (pH 8.0) containing 10% glycerol, 0.1M NaCl.

Purity/Purification

> 95% by SDS-PAGE

Concentration

0.25mg/ml (determined by Absorbance at 280nm) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

46.6kDa (433aa) 40-57kDa (SDS-PAGE under reducing conditions.)

OMIM

L33799 mRNA

3D Structure

ModBase 3D Structure for Q15113

Antigen Species

Human

Tag Information

His-tag

Endotoxin Level

< 1.0 EU per 1ug of protein (determined by LAL method)

Product Categories/Family for PCOLCE recombinant protein

Signal Transduction; Cytoskeleton

Applications Tested/Suitable for PCOLCE recombinant protein

SDS-PAGE

Product References and Citations for PCOLCE recombinant protein

Takahara K., et al, (1994) J. Biol. Chem. 269:26280-26285. Scott IC., et al, (1999) Genomics 55:229-234.

Other Notes

Small volumes of PCOLCE recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PCOLCE purchase

MBS206814 is a recombinant protein targeting PCOLCE. Also known as PCOLCE, 26-449aa, Human, His-tag, Baculovirus. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for PCOLCE. It may not necessarily be applicable to this product.

NCBI GI #

157653329

NCBI GeneID

5118

NCBI Accession #

NP_002584

UniProt Primary Accession #

Q15113

UniProt Secondary Accession #

O14550; B2R9E1

UniProt Related Accession #

Q15113

GenBank Nucleotide #

NM_002593.3

NCBI Official Full Name

procollagen C-endopeptidase enhancer 1

NCBI Official Synonym Full Names

procollagen C-endopeptidase enhancer

NCBI Official Symbol

PCOLCE

NCBI Official Synonym Symbols

PCPE; PCPE1; PCPE-1

UniProt Protein Name

Procollagen C-endopeptidase enhancer 1

UniProt Synonym Protein Names

Procollagen COOH-terminal proteinase enhancer 1; PCPE-1; Procollagen C-proteinase enhancer 1; Type 1 procollagen C-proteinase enhancer protein; Type I procollagen COOH-terminal proteinase enhancer

Protein Family

Procollagen C-endopeptidase enhancer

UniProt Gene Name

PCOLCE

UniProt Synonym Gene Names

PCPE1; PCPE-1; Procollagen C-proteinase enhancer 1

NCBI Protein Information

procollagen C-endopeptidase enhancer 1

NCBI Summary for PCOLCE

Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity. [provided by RefSeq, Jul 2008]

UniProt Comments for PCOLCE

Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity.

Research Articles on PCOLCE

1. Results suggest that PCPE-1 binding to syndecans and/or fibronectin may control collagen fibril assembly on the cell surface.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PCOLCE recombinant protein

Reference Product	PubMed Publications
COL1A2 recombinant protein	>3 publications with PCOLCE and COL1A2

Pathways associated with PCOLCE recombinant protein

Products by Pathway	Pathway Diagram
Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies	Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
Collagen Biosynthesis And Modifying Enzymes Pathway antibodies	Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
Collagen Formation Pathway antibodies	Collagen Formation Pathway Diagram
Crosslinking Of Collagen Fibrils Pathway antibodies	Crosslinking Of Collagen Fibrils Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram

Diseases associated with PCOLCE recombinant protein

Disease Name	Pubmed Publications
Fibrosis Antibodies	>10 publications with PCOLCE and Fibrosis
Nervous System Diseases Antibodies	>5 publications with PCOLCE and Nervous System Diseases
Heart Diseases Antibodies	>3 publications with PCOLCE and Heart Diseases
Inflammation Antibodies	>3 publications with PCOLCE and Inflammation
Necrosis Antibodies	>3 publications with PCOLCE and Necrosis
Liver Diseases Antibodies	>2 publications with PCOLCE and Liver Diseases
Liver Cirrhosis Antibodies	>2 publications with PCOLCE and Liver Cirrhosis
Skin Diseases Antibodies	>1 publications with PCOLCE and Skin Diseases
Breast Neoplasms Antibodies	>1 publications with PCOLCE and Breast Neoplasms
Hyperplasia Antibodies	>1 publications with PCOLCE and Hyperplasia

Organs/Tissues associated with PCOLCE recombinant protein

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>34 publications with PCOLCE and Bone
Muscle Antibodies	>9 publications with PCOLCE and Muscle
Heart Antibodies	>8 publications with PCOLCE and Heart
Connective Tissue Antibodies	>8 publications with PCOLCE and Connective Tissue
Eye Antibodies	>5 publications with PCOLCE and Eye
Embryonic Tissue Antibodies	>5 publications with PCOLCE and Embryonic Tissue
Liver Antibodies	>5 publications with PCOLCE and Liver
Vascular Antibodies	>4 publications with PCOLCE and Vascular
Kidney Antibodies	>3 publications with PCOLCE and Kidney
Brain Antibodies	>3 publications with PCOLCE and Brain