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Leucyl Trna Synthetase (LARS) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2069360
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2069360 is an antibody targeting LARS. Also known as APC/CY7-Linked Polyclonal Antibody to Leucyl tRNA Synthetase (LARS). Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$445 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Leucyl tRNA Synthetase (LARS), Polyclonal Antibody
Full Product Name
APC/CY7-Linked Polyclonal Antibody to Leucyl tRNA Synthetase (LARS)
Product Gene Name
Product Synonym Names
LEURS; LARS1; LEUS; RNTLS; Leucine tRNA Ligase 1, Cytoplasmic
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Concentration
>=100ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: LARS (MBS2033763)
APC-CY7 Conjugated Antibody: LARS (MBS2069360)
Molecular Weight
55,295 Da
OMIM
D84223 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
LARS (Gly260~Glu509)
Conjugation
APC-Cy7
Cross Reactivity
Human, Mouse
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2033763
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-LARS antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-LARS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LARS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
leucyl tRNA synthetase
NCBI Official Synonym Full Names
leucyl-tRNA synthetase
NCBI Official Symbol
LARS
NCBI Official Synonym Symbols
LRS; LEUS; LFIS; ILFS1; LARS1; LEURS; PIG44; RNTLS; HSPC192; hr025Cl
UniProt Protein Name
Leucine--tRNA ligase, cytoplasmic
UniProt Synonym Protein Names
Leucyl-tRNA synthetase; LeuRS
Protein Family
UniProt Gene Name
LARS
UniProt Synonym Gene Names
KIAA1352; LeuRS
NCBI Protein Information
leucine--tRNA ligase, cytoplasmic

NCBI Summary for LARS

This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed. [provided by RefSeq, Dec 2015]
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UniProt Comments for LARS

LARS: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs. Belongs to the class-I aminoacyl-tRNA synthetase family.

Protein type: Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; EC 6.1.1.4; Ligase; Translation

Chromosomal Location of Human Ortholog: 5q32

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: leucine-tRNA ligase activity; protein binding

Biological Process: leucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation

Disease: Infantile Liver Failure Syndrome 1
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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