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Hypoxia Inducible Factor 2 Alpha (HIF2a) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2071619
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MBS2071619 is an antibody targeting HIF2a. Also known as HRP-Linked Polyclonal Antibody to Hypoxia Inducible Factor 2 Alpha (HIF2a). Reactive in Rat, Human, Mouse. Host: Rabbit. More details

$270 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Hypoxia Inducible Factor 2 Alpha (HIF2a), Polyclonal Antibody
Full Product Name
HRP-Linked Polyclonal Antibody to Hypoxia Inducible Factor 2 Alpha (HIF2a)
Product Gene Name
Product Synonym Names
EPAS1; HLF; MOP2; PASD2; BHLHE73; Endothelial PAS Domain 1; HIF-1 Alpha-Like Factor; Basic-helix-loop-helix-PAS protein MOP2; Class E basic helix-loop-helix protein 73
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat, Human, Mouse
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: HIF2a (MBS2004014)
HRP Conjugated Antibody: HIF2a (MBS2071619)
Matching Pairs
HRP Conjugated Antibody: HIF2a (MBS2071619)
Immunogen: HIF2a (MBS2011699)
Molecular Weight
96,718 Da
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
HIF2a (Arg24~Glu348)
Conjugation
HRP
Cross Reactivity
Rat
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2004014
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-HIF2a antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-HIF2a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HIF2a. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
NCBI Official Full Name
hypoxia inducible factor 2 alpha
NCBI Official Synonym Full Names
endothelial PAS domain protein 1
NCBI Official Symbol
Epas1
NCBI Official Synonym Symbols
HLF; Hif2a; HIF2 alpha; HIF-2 alpha
UniProt Protein Name
Endothelial PAS domain-containing protein 1
UniProt Synonym Protein Names
Hypoxia-inducible factor 2-alpha; HIF-2-alpha; HIF2-alpha
UniProt Gene Name
Epas1
UniProt Synonym Gene Names
Hif2a; EPAS-1; HIF-2-alpha; HIF2-alpha
NCBI Protein Information
endothelial PAS domain-containing protein 1

NCBI Summary for HIF2a

activates luciferase activity after transfection [RGD, Feb 2006]

UniProt Comments for HIF2a

Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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