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Phospholipase A2, Group III (PLA2G3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2073100
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2073100 is an antibody targeting PLA2G3. Also known as HRP-Linked Polyclonal Antibody to Phospholipase A2, Group III (PLA2G3). Reactive in Human. Host: Rabbit. More details

$250 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Phospholipase A2, Group III (PLA2G3), Polyclonal Antibody
Full Product Name
HRP-Linked Polyclonal Antibody to Phospholipase A2, Group III (PLA2G3)
Product Gene Name
anti-PLA2G3 antibody
Product Synonym Names
GIII-SPLA2; sPLA2-III; Group 3 secretory phospholipase A2; Group III secretory phospholipase A2; Phosphatidylcholine 2-acylhydrolase 3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: PLA2G3 (MBS2034001)
HRP Conjugated Antibody: PLA2G3 (MBS2073100)
Matching Pairs
HRP Conjugated Antibody: PLA2G3 (MBS2073100)
Immunogen: PLA2G3 (MBS2034286)
Molecular Weight
57,167 Da
OMIM
AF220490 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
PLA2G3 (Gly20~Val268)
Conjugation
HRP
Cross Reactivity
Human
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2034001
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PLA2G3 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-PLA2G3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLA2G3. It may not necessarily be applicable to this product.

NCBI GI #
119580345
NCBI GeneID
50487
NCBI Accession #
EAW59941.1
UniProt Secondary Accession #
O95768
UniProt Related Accession #
Q9NZ20
NCBI Official Full Name
phospholipase A2, group III
NCBI Official Synonym Full Names
phospholipase A2 group III
NCBI Official Symbol
PLA2G3
NCBI Official Synonym Symbols
SPLA2III; sPLA2-III; GIII-SPLA2
UniProt Protein Name
Group 3 secretory phospholipase A2
UniProt Synonym Protein Names
Group III secretory phospholipase A2; GIII sPLA2; sPLA2-III; Phosphatidylcholine 2-acylhydrolase 3
Protein Family
Group 3 secretory phospholipase
UniProt Gene Name
PLA2G3
UniProt Synonym Gene Names
GIII sPLA2; sPLA2-III
NCBI Protein Information
group 3 secretory phospholipase A2

NCBI Summary for PLA2G3

This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease. [provided by RefSeq, Apr 2014]
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UniProt Comments for PLA2G3

PLA2G3: PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Shows an 11-fold preference for phosphatidylglycerol over phosphatidylcholine (PC). Preferential cleavage: 1-palmitoyl-2-linoleoyl- phosphatidylethanolamine (PE) > 1-palmitoyl-2-linoleoyl-PC > 1- palmitoyl-2-arachidonoyl-PC > 1-palmitoyl-2-arachidonoyl-PE. Plays a role in ciliogenesis. Belongs to the phospholipase A2 family.

Protein type: EC 3.1.1.4; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - arachidonic acid; Lipid Metabolism - ether lipid; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - linoleic acid; Phospholipase

Chromosomal Location of Human Ortholog: 22q12.2

Cellular Component: centriole; extracellular region; extracellular space

Molecular Function: calcium-dependent phospholipase A2 activity; phospholipase A2 activity

Biological Process: phospholipid metabolic process
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Research Articles on PLA2G3

1. Studies indicate that the expression of secreted phospholipases A2 (sPLA2s), most notably the group IIA, III and X enzymes, is dysregulated in various malignant tissues.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLA2G3 antibody

 Reference Product  PubMed Publications
 PLA2G7 antibody  >1 publications with PLA2G3 and PLA2G7
 PLA2G15 antibody  >1 publications with PLA2G3 and PLA2G15
 PTGS2 antibody  >1 publications with PLA2G3 and PTGS2

Pathways associated with anti-PLA2G3 antibody

 Products by Pathway  Pathway Diagram
 Acyl Chain Remodelling Of PC Pathway antibodies  Acyl Chain Remodelling Of PC Pathway Diagram
 Acyl Chain Remodelling Of PE Pathway antibodies  Acyl Chain Remodelling Of PE Pathway Diagram
 Acyl Chain Remodelling Of PG Pathway antibodies  Acyl Chain Remodelling Of PG Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram

Diseases associated with anti-PLA2G3 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >3 publications with PLA2G3 and Inflammation
 Nervous System Diseases Antibodies  >2 publications with PLA2G3 and Nervous System Diseases
 Adenocarcinoma Antibodies  >2 publications with PLA2G3 and Adenocarcinoma
 Brain Diseases Antibodies  >2 publications with PLA2G3 and Brain Diseases
 Uterine Neoplasms Antibodies  >1 publications with PLA2G3 and Uterine Neoplasms
 Hyperplasia Antibodies  >1 publications with PLA2G3 and Hyperplasia
 Necrosis Antibodies  >1 publications with PLA2G3 and Necrosis

Organs/Tissues associated with anti-PLA2G3 antibody

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >1 publications with PLA2G3 and Intestine
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