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17-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD17b3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2076029
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MBS2076029 is an antibody targeting HSD17b3. Also known as APC-Linked Polyclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD17b3). Reactive in Human, Mouse, Rabbit. Host: Rabbit. More details

$330 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
17-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD17b3), Polyclonal Antibody
Full Product Name
APC-Linked Polyclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD17b3)
Product Gene Name
anti-HSD17b3 antibody
Product Synonym Names
SDR12C2; EDH17B3; Short Chain Dehydrogenase/Reductase Family 12C, Member 2; Testosterone 17-Beta-Dehydrogenase 3; Testicular 17-beta-hydroxysteroid dehydrogenase
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rabbit
Concentration
>=100ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: HSD17b3 (MBS2033852)
APC Conjugated Antibody: HSD17b3 (MBS2076029)
Matching Pairs
APC Conjugated Antibody: HSD17b3 (MBS2076029)
Immunogen: HSD17b3 (MBS2034334)
Molecular Weight
34,330 Da
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
HSD17b3 (Met1~Arg310)
Conjugation
APC
Cross Reactivity
Human
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2033852
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-HSD17b3 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-HSD17b3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HSD17b3. It may not necessarily be applicable to this product.

NCBI GI #
1513310
NCBI GeneID
15487
NCBI Accession #
AAB06793.1
UniProt Secondary Accession #
G3UWF9
UniProt Related Accession #
P70385
NCBI Official Full Name
17-beta-hydroxysteroid dehydrogenase type 3
NCBI Official Synonym Full Names
hydroxysteroid (17-beta) dehydrogenase 3
NCBI Official Symbol
Hsd17b3
UniProt Protein Name
Testosterone 17-beta-dehydrogenase 3
UniProt Synonym Protein Names
17-beta-hydroxysteroid dehydrogenase type 3; 17-beta-HSD 3; Testicular 17-beta-hydroxysteroid dehydrogenase
Protein Family
Testosterone 17-beta-dehydrogenase
UniProt Gene Name
Hsd17b3
UniProt Synonym Gene Names
Edh17b3; 17-beta-HSD 3
NCBI Protein Information
testosterone 17-beta-dehydrogenase 3

UniProt Comments for HSD17b3

HSD17B3: Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH. Defects in HSD17B3 are the cause of male pseudohermaphrodism with gynecomastia (MPH). These individuals have unambiguous female external genitalia at birth, but fail to menstruate at the time of expected puberty and instead virilize as evidenced by growth of the phallus. Breast development may or may not take place. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.

Protein type: EC 1.1.1.64; Lipid Metabolism - androgen and estrogen; Oxidoreductase

Chromosomal Location of Human Ortholog: 13|13 B3

Cellular Component: endoplasmic reticulum; intracellular membrane-bound organelle

Molecular Function: 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity; estradiol 17-beta-dehydrogenase activity; testosterone 17-beta-dehydrogenase (NADP+) activity

Biological Process: steroid biosynthetic process
Show more

Research Articles on HSD17b3

1. Enzyme activities of 3-betaHSDH increase as the sound pressure levels increase in adrenal cortex zona fasciculate polygonal cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HSD17b3 antibody

 Reference Product  PubMed Publications
 Srd5a2 antibody  >15 publications with HSD17b3 and Srd5a2
 Cyp19a1 antibody  >13 publications with HSD17b3 and Cyp19a1
 Hsd3b1 antibody  >12 publications with HSD17b3 and Hsd3b1
 Srd5a1 antibody  >8 publications with HSD17b3 and Srd5a1
 Hsd3b2 antibody  >5 publications with HSD17b3 and Hsd3b2
 Cyp11b2 antibody  >4 publications with HSD17b3 and Cyp11b2
 Hsd3b6 antibody  >4 publications with HSD17b3 and Hsd3b6

Pathways associated with anti-HSD17b3 antibody

 Products by Pathway  Pathway Diagram
 Androgen Biosynthesis Pathway antibodies  Androgen Biosynthesis Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Metabolism Of Steroid Hormones And Vitamin D Pathway antibodies  Metabolism Of Steroid Hormones And Vitamin D Pathway Diagram
 Steroid Biosynthesis Pathway antibodies  Steroid Biosynthesis Pathway Diagram
 Steroid Hormone Biosynthesis Pathway antibodies  Steroid Hormone Biosynthesis Pathway Diagram
 Steroid Hormone Biosynthesis Pathway antibodies  Steroid Hormone Biosynthesis Pathway Diagram
 Biosynthesis Of Androgens Pathway antibodies  Biosynthesis Of Androgens Pathway Diagram

Diseases associated with anti-HSD17b3 antibody

 Disease Name  Pubmed Publications
 Urogenital Abnormalities Antibodies  >21 publications with HSD17b3 and Urogenital Abnormalities
 Disorders of Sex Development Antibodies  >19 publications with HSD17b3 and Disorders of Sex Development
 Genital Diseases, Male Antibodies  >15 publications with HSD17b3 and Genital Diseases, Male
 Prostatic Diseases Antibodies  >10 publications with HSD17b3 and Prostatic Diseases
 Prostatic Neoplasms Antibodies  >9 publications with HSD17b3 and Prostatic Neoplasms
 Hyperplasia Antibodies  >4 publications with HSD17b3 and Hyperplasia
 Ovarian Diseases Antibodies  >3 publications with HSD17b3 and Ovarian Diseases
 Prenatal Exposure Delayed Effects Antibodies  >3 publications with HSD17b3 and Prenatal Exposure Delayed Effects
 Infertility, Male Antibodies  >3 publications with HSD17b3 and Infertility, Male
 17-Hydroxysteroid Dehydrogenase Deficiency Antibodies  >2 publications with HSD17b3 and 17-Hydroxysteroid Dehydrogenase Deficiency

Organs/Tissues associated with anti-HSD17b3 antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >28 publications with HSD17b3 and Testis
 Uncharacterized Tissue Antibodies  >1 publications with HSD17b3 and Uncharacterized Tissue
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