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Alpha-Tocopherol Transfer Protein (TTPa) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2079033
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MBS2079033 is an antibody targeting TTPa. Also known as APC/CY7-Linked Polyclonal Antibody to Alpha-Tocopherol Transfer Protein (TTPa). Reactive in Mouse, Human, Rat. Host: Rabbit. More details

$455 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Alpha-Tocopherol Transfer Protein (TTPa), Polyclonal Antibody
Full Product Name
APC/CY7-Linked Polyclonal Antibody to Alpha-Tocopherol Transfer Protein (TTPa)
Product Gene Name
Product Synonym Names
AVED; TTP1; alphaTTP; Ataxia (Friedreich-Like)With Vitamin E Deficiency
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Human, Rat
Concentration
>=100ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: TTPa (MBS2027405)
APC-CY7 Conjugated Antibody: TTPa (MBS2079033)
Matching Pairs
APC-CY7 Conjugated Antibody: TTPa (MBS2079033)
Immunogen: TTPa (MBS2031075)
Molecular Weight
31,750 Da
OMIM
D49488 mRNA
3D Structure
ModBase 3D Structure for P49638
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
TTPa (Arg88~Glu253)
Conjugation
APC-Cy7
Cross Reactivity
Mouse
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2027405
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-TTPa antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-TTPa antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TTPa. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
alpha-tocopherol transfer protein
NCBI Official Synonym Full Names
alpha tocopherol transfer protein
NCBI Official Symbol
TTPA
NCBI Official Synonym Symbols
ATTP; AVED; TTP1; alphaTTP
UniProt Protein Name
Alpha-tocopherol transfer protein
UniProt Gene Name
TTPA
UniProt Synonym Gene Names
TPP1; Alpha-TTP
NCBI Protein Information
alpha-tocopherol transfer protein

NCBI Summary for TTPa

This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa. [provided by RefSeq, Nov 2009]
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UniProt Comments for TTPa

TTPA: Binds alpha-tocopherol and enhances its transfer between separate membranes. Defects in TTPA are the cause of ataxia with isolated vitamin E deficiency (AVED). AVED is an autosomal recessive disease characterized by spinocerebellar degeneration. It causes ataxia and peripheral neuropathy that resembles Friedreich ataxia. AVED patients have markedly reduced plasma levels of vitamin E.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 8q12.3

Molecular Function: phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding; vitamin E binding

Biological Process: intermembrane transport; lipid metabolic process; transport; vitamin transport

Disease: Vitamin E, Familial Isolated Deficiency Of
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TTPa antibody

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