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Myotrophin (MTPN) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2080039
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MBS2080039 is an antibody targeting MTPN. Also known as APC/CY7-Linked Polyclonal Antibody to Myotrophin (MTPN). Reactive in Mouse, Human, Rat. Host: Rabbit. More details

$455 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Myotrophin (MTPN), Polyclonal Antibody
Full Product Name
APC/CY7-Linked Polyclonal Antibody to Myotrophin (MTPN)
Product Gene Name
Product Synonym Names
GCDP; V-1; Granule Cell Differentiation Protein
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Human, Rat
Concentration
>=100ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: MTPN (MBS2032117)
APC-CY7 Conjugated Antibody: MTPN (MBS2080039)
Matching Pairs
APC-CY7 Conjugated Antibody: MTPN (MBS2080039)
Immunogen: MTPN (MBS2033383)
Molecular Weight
12,895 Da
OMIM
AC015987 Genomic DNA
3D Structure
ModBase 3D Structure for P58546
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
MTPN (Cys2~Gln118)
Conjugation
APC-Cy7
Cross Reactivity
Mouse
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2032117
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-MTPN antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-MTPN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MTPN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
myotrophin
NCBI Official Synonym Full Names
myotrophin
NCBI Official Symbol
MTPN
NCBI Official Synonym Symbols
V-1; GCDP
UniProt Protein Name
Myotrophin
UniProt Synonym Protein Names
Protein V-1
Protein Family
UniProt Gene Name
MTPN
NCBI Protein Information
myotrophin

NCBI Summary for MTPN

The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008]
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UniProt Comments for MTPN

MTPN: Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Belongs to the myotrophin family.

Chromosomal Location of Human Ortholog: 7q33

Cellular Component: cytosol; F-actin capping protein complex; nucleus

Biological Process: activation of NF-kappaB transcription factor; cell growth; positive regulation of cell growth; positive regulation of protein metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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