NP_000756.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
61,547 Da
NCBI Official Full Name
cytochrome P450 3A7
NCBI Official Synonym Full Names
cytochrome P450 family 3 subfamily A member 7
NCBI Official Synonym Symbols
CP37; CYPIIIA7; P450-HFLA; P-450111A7; P-450(HFL33) [Similar Products]
NCBI Protein Information
cytochrome P450 3A7
UniProt Protein Name
Cytochrome P450 3A7
UniProt Synonym Protein Names
CYPIIIA7; Cytochrome P450-HFLA
NCBI Summary for CYP3A7
This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540. [provided by RefSeq, Jan 2015]
UniProt Comments for CYP3A7
CYP3A7: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Belongs to the cytochrome P450 family.
Protein type: Cofactor and Vitamin Metabolism - retinol; EC 1.14.14.1; Lipid Metabolism - linoleic acid; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - drug metabolism - other enzymes; Xenobiotic Metabolism - metabolism by cytochrome P450
Chromosomal Location of Human Ortholog: 7q22.1
Cellular Component: endoplasmic reticulum membrane
Molecular Function: monooxygenase activity; oxygen binding; steroid hydroxylase activity
Biological Process: steroid metabolic process; xenobiotic metabolic process
Research Articles on CYP3A7
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Products associated with anti-CYP3A7 antibody
Pathways associated with anti-CYP3A7 antibody
Organs/Tissues associated with anti-CYP3A7 antibody
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