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Mucin 20 (MUC20) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2092750
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MBS2092750 is an antibody targeting MUC20. Also known as Biotin-Linked Polyclonal Antibody to Mucin 20 (MUC20). Reactive in Rat. Host: Rabbit. More details

$220 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Mucin 20 (MUC20), Polyclonal Antibody
Full Product Name
Biotin-Linked Polyclonal Antibody to Mucin 20 (MUC20)
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: MUC20 (MBS2026746)
Biotin Conjugated Antibody: MUC20 (MBS2092750)
Matching Pairs
Biotin Conjugated Antibody: MUC20 (MBS2092750)
Immunogen: MUC20 (MBS2031435)
Molecular Weight
68,308 Da
OMIM
AB098731 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
Biotin
Cross Reactivity
Rat
Immunogen
MUC20 (Thr113~Asn347)
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-MUC20 antibody
Western Blot (WB), Immunohistochemistry (IHC)

Other Notes

Small volumes of anti-MUC20 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MUC20. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
mucin 20, partial
NCBI Official Synonym Full Names
mucin 20, cell surface associated
NCBI Official Symbol
MUC20
NCBI Official Synonym Symbols
MUC-20
UniProt Protein Name
Mucin-20
Protein Family
UniProt Gene Name
MUC20
UniProt Synonym Gene Names
KIAA1359; MUC-20
NCBI Protein Information
mucin-20

NCBI Summary for MUC20

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The C-terminus of this family member associates with the multifunctional docking site of the MET proto-oncogene and suppresses activation of some downstream MET signaling cascades. The protein features a mucin tandem repeat domain that varies between two and six copies in most individuals. Multiple variants encoding different isoforms have been found for this gene. A related pseudogene, which is also located on chromosome 3, has been identified. [provided by RefSeq, Apr 2014]
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UniProt Comments for MUC20

MUC20: May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: apical plasma membrane; basal plasma membrane; extracellular region; Golgi lumen; microvillus membrane; plasma membrane

Biological Process: activation of MAPK activity; hepatocyte growth factor receptor signaling pathway; O-glycan processing; protein homooligomerization; stimulatory C-type lectin receptor signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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