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Calcium Modulating Ligand (CAMLG) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2094430
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2094430 is an antibody targeting CAMLG. Also known as Biotin-Linked Polyclonal Antibody to Calcium Modulating Ligand (CAMLG). Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$225 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Calcium Modulating Ligand (CAMLG), Polyclonal Antibody
Full Product Name
Biotin-Linked Polyclonal Antibody to Calcium Modulating Ligand (CAMLG)
Product Gene Name
Product Synonym Names
CAML; Calcium Signal-Modulating Cyclophilin Ligand; Calcium-Signal Modulating Cyclophilin Ligand; Cyclophilin B-Binding Protein
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: CAMLG (MBS2032668)
Biotin Conjugated Antibody: CAMLG (MBS2094430)
Matching Pairs
Biotin Conjugated Antibody: CAMLG (MBS2094430)
Immunogen: CAMLG (MBS2033627)
Molecular Weight
32,953 Da
OMIM
U18242 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
Biotin
Cross Reactivity
Human, Mouse, Rat
Immunogen
CAMLG (Gly19~Glu184)
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CAMLG antibody
Western Blot (WB), Immunohistochemistry (IHC)

Knockout Validation of anti-CAMLG antibody

Knockout Validation: Lane 1: Wild-type Jurkat cell lysate; Lane 2: CAMLG knockout Jurkat cell lysate; Predicted MW: 33kd Observed MW: 37kd Primary Ab: 1ug/ml Rabbit Anti-Human CAMLG Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047)
Rabbit Anti-CAMLG Polyclonal Antibody – Cat# MBS2094430

Other Notes

Small volumes of anti-CAMLG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CAMLG. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Calcium modulating ligand
NCBI Official Synonym Full Names
calcium modulating ligand
NCBI Official Symbol
CAMLG
NCBI Official Synonym Symbols
CAML; GET2
UniProt Protein Name
Calcium signal-modulating cyclophilin ligand
UniProt Gene Name
CAMLG
UniProt Synonym Gene Names
CAML; CAML
NCBI Protein Information
calcium signal-modulating cyclophilin ligand

NCBI Summary for CAMLG

The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008]
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UniProt Comments for CAMLG

CAMLG: Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.

Protein type: Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: endoplasmic reticulum; integral component of membrane; membrane

Molecular Function: cell adhesion molecule binding; protein binding

Biological Process: defense response; epidermal growth factor receptor signaling pathway; receptor recycling; signal transduction; viral process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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