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Thimet Oligopeptidase 1 (THOP1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2096329
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MBS2096329 is an antibody targeting THOP1. Also known as Biotin-Linked Polyclonal Antibody to Thimet Oligopeptidase 1 (THOP1). Reactive in Human, Mouse, Rat, Pig. Host: Rabbit. More details

$225 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Thimet Oligopeptidase 1 (THOP1), Polyclonal Antibody
Full Product Name
Biotin-Linked Polyclonal Antibody to Thimet Oligopeptidase 1 (THOP1)
Product Gene Name
Product Synonym Names
EP24.15; MEPD_HUMAN; MP78; Endopeptidase 24.15
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Pig
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: THOP1 (MBS2028241)
Biotin Conjugated Antibody: THOP1 (MBS2096329)
Matching Pairs
Biotin Conjugated Antibody: THOP1 (MBS2096329)
Immunogen: THOP1 (MBS2029722)
Molecular Weight
28,908 Da
OMIM
Z50115 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
Biotin
Cross Reactivity
Human, Mouse, Pig
Immunogen
THOP1 (Asn451~Thr597)
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-THOP1 antibody
Western Blot (WB), Immunohistochemistry (IHC)

Other Notes

Small volumes of anti-THOP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for THOP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Thimet oligopeptidase 1
NCBI Official Synonym Full Names
thimet oligopeptidase 1
NCBI Official Symbol
THOP1
NCBI Official Synonym Symbols
TOP; MP78; EP24.15; MEPD_HUMAN
UniProt Protein Name
Thimet oligopeptidase
UniProt Synonym Protein Names
Endopeptidase 24.15; MP78
Protein Family
UniProt Gene Name
THOP1
NCBI Protein Information
thimet oligopeptidase

NCBI Summary for THOP1

The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015]
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UniProt Comments for THOP1

THOP1: a protease that cleaves preferentially bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues. Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.

Protein type: EC 3.4.24.15; Protease

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cytosol; mitochondrial intermembrane space

Molecular Function: metal ion binding; metalloendopeptidase activity; peptide binding

Biological Process: peptide metabolic process; protein polyubiquitination; proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-THOP1 antibody

 Reference Product  PubMed Publications
 AGTR1 antibody  >1 publications with THOP1 and AGTR1
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