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Metastasis Associated in Colon Cancer 1 (MACC1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2096976
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MBS2096976 is an antibody targeting MACC1. Also known as Biotin-Linked Polyclonal Antibody to Metastasis Associated In Colon Cancer 1 (MACC1). Reactive in Human, Pig. Host: Rabbit. More details

$235 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Metastasis Associated In Colon Cancer 1 (MACC1), Polyclonal Antibody
Full Product Name
Biotin-Linked Polyclonal Antibody to Metastasis Associated In Colon Cancer 1 (MACC1)
Product Gene Name
Product Synonym Names
7A5; SH3BP4L; SH3 domain-containing protein 7a5
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Pig
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: MACC1 (MBS2003284)
Biotin Conjugated Antibody: MACC1 (MBS2096976)
Matching Pairs
Biotin Conjugated Antibody: MACC1 (MBS2096976)
Immunogen: MACC1 (MBS2010192)
Molecular Weight
96,639 Da
OMIM
AJ313524 mRNA
3D Structure
ModBase 3D Structure for Q6ZN28
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
Biotin
Cross Reactivity
Human
Immunogen
MACC1 (Gln522-Met784)
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-MACC1 antibody
Western Blot (WB), Immunohistochemistry (IHC)

Other Notes

Small volumes of anti-MACC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MACC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
metastasis-associated in colon cancer protein 1
NCBI Official Synonym Full Names
MACC1, MET transcriptional regulator
NCBI Official Symbol
MACC1
NCBI Official Synonym Symbols
7A5; SH3BP4L
UniProt Protein Name
Metastasis-associated in colon cancer protein 1
UniProt Synonym Protein Names
SH3 domain-containing protein 7a5
UniProt Gene Name
MACC1
NCBI Protein Information
metastasis-associated in colon cancer protein 1

NCBI Summary for MACC1

MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009]
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UniProt Comments for MACC1

MACC1: Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo.

Chromosomal Location of Human Ortholog: 7p21.1

Cellular Component: cytoplasm; mitochondrion; nucleus

Molecular Function: growth factor activity

Biological Process: positive regulation of cell division; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MACC1 antibody

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