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Osteoclast Associated Receptor (OSCAR) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2109676
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MBS2109676 is an antibody targeting OSCAR. Also known as FITC-Linked Monoclonal Antibody to Osteoclast Associated Receptor (OSCAR). Reactive in Human. Host: Mouse. More details

$275 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Osteoclast Associated Receptor (OSCAR), Monoclonal Antibody
Full Product Name
FITC-Linked Monoclonal Antibody to Osteoclast Associated Receptor (OSCAR)
Product Gene Name
Product Synonym Names
PIGR3; Osteoclast Associated, Immunoglobulin-Like Receptor; Polymeric immunoglobulin receptor 3; Poly-Ig receptor 3
Immunogen Sequence
RPC695Hu01 -Recombina nt Osteoclast Associated Receptor (OSCAR)
Clonality
Monoclonal
Isotype
IgG1 Kappa
Clone Number
C2
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
500ug/ml (lot specific)
Specificity
The antibody is a Mouse monoclonal antibody raised against OSCAR. It has been selected for its ability to recognize OSCAR in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: OSCAR Clone #C2 (MBS2090644)
FITC Conjugated Antibody: OSCAR Clone #C2 (MBS2109676)
Matching Pairs
FITC Conjugated Antibody: OSCAR Clone #C2 (MBS2109676)
Immunogen: OSCAR (MBS2105198)
OMIM
606862
3D Structure
ModBase 3D Structure for Q8IYS5
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
FITC
Cross Reactivity
Human
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-OSCAR antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Other Notes

Small volumes of anti-OSCAR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for OSCAR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Osteoclast-associated immunoglobulin-like receptor
NCBI Official Synonym Full Names
osteoclast associated Ig-like receptor
NCBI Official Symbol
OSCAR
NCBI Official Synonym Symbols
PIGR3; PIgR-3
UniProt Protein Name
Osteoclast-associated immunoglobulin-like receptor
UniProt Synonym Protein Names
Polymeric immunoglobulin receptor 3
UniProt Gene Name
OSCAR
UniProt Synonym Gene Names
Osteoclast-associated receptor; hOSCAR; PIgR-3; PIgR3
UniProt Entry Name
OSCAR_HUMAN
NCBI Protein Information
osteoclast-associated immunoglobulin-like receptor

NCBI Summary for OSCAR

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
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UniProt Comments for OSCAR

OSCAR: Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation. Belongs to the leukocyte receptor complex/polymeric immunogobulin receptor (PIR/LRC) family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: plasma membrane; integral to membrane
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-OSCAR antibody

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