Hamster Anti-EMR3 Monoclonal Antibody – Cat# MBS210982

EMR3 Antibody – Hamster Monoclonal

Name: EMR3 Antibody; Monoclonal; Hamster; MyBioSource
Brand: MyBioSource
SKU: MBS210982
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS210982

Hamster anti Human EMR3 antibody, clone 3D7 recognizes human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), which is a 56kD member of the EGF-7 transmembrane (TM7) family of adhesion receptors. EMR3 is expressed at the… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

EMR3, Monoclonal Antibody

Full Product Name

HAMSTER ANTI HUMAN EMR3:FITC

Product Gene Name

anti-EMR3 antibody

Clonality

Monoclonal

Isotype

IgG

Clone Number

3D7

Host

Hamster

Form/Format

FITC
Purified IgG - liquid

Concentration

IgG concentration 0.1 mg/ml (lot specific)

Preparation and Storage

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Molecular Weight

6,996 Da

OMIM

606101

3D Structure

ModBase 3D Structure for Q9BY15

Perservative Stabilisers

0.09% Sodium Azide
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen

ARHO-EMR3-CD97 (EGF1) transfectants.
Fusion Partners||Spleen cells from immunised Armenian hamster were fused with cells of the mouse SP2/0 myeloma cell line.
Buffer Solution||Phosphate buffered saline

Target Species

Human

Applications Tested/Suitable for anti-EMR3 antibody

Flow cytometry (FC/FACS)

Application Notes for anti-EMR3 antibody

Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10

Other Notes

Small volumes of anti-EMR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EMR3 purchase

MBS210982 is an antibody targeting EMR3. Also known as HAMSTER ANTI HUMAN EMR3:FITC. Host: Hamster.

Additional Details

NCBI/Uniprot data below describe general gene information for EMR3. It may not necessarily be applicable to this product.

NCBI GI #

574584843

NCBI GeneID

84658

NCBI Accession #

NP_001276087.1

UniProt Primary Accession #

Q9BY15

UniProt Related Accession #

Q9BY15

GenBank Nucleotide #

NM_001289158.1

NCBI Official Full Name

EGF-like module-containing mucin-like hormone receptor-like 3 isoform 2

NCBI Official Synonym Full Names

egf-like module containing, mucin-like, hormone receptor-like 3

NCBI Official Symbol

EMR3

UniProt Protein Name

EGF-like module-containing mucin-like hormone receptor-like 3

UniProt Synonym Protein Names

EGF-like module receptor 3Cleaved into the following 2 chains:EGF-like module-containing mucin-like hormone receptor-like 3 subunit alpha; EGF-like module-containing mucin-like hormone receptor-like 3 subunit beta

UniProt Gene Name

EMR3

UniProt Entry Name

EMR3_HUMAN

NCBI Protein Information

EGF-like module-containing mucin-like hormone receptor-like 3; EGF-like module receptor 3; egf-like module-containing mucin-like receptor 3

NCBI Summary for EMR3

This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014]

UniProt Comments for EMR3

EMR3: Receptor probably involved in myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of momocytes- derived macrophages and activated neutrophils. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 2

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: extracellular space; integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; calcium ion binding

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on EMR3

1. Given the poor survival associated with high levels of EMR-3 expression in glioma patients, impetus is provided to explore EMR-3 as a potential therapeutic target.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-EMR3 antibody

Products by Pathway	Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Other Pathway antibodies	GPCRs, Other Pathway Diagram
Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies	Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with anti-EMR3 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>5 publications with EMR3 and Inflammation
Immune System Diseases Antibodies	>3 publications with EMR3 and Immune System Diseases
Cardiovascular Diseases Antibodies	>1 publications with EMR3 and Cardiovascular Diseases
Neoplasm Invasiveness Antibodies	>1 publications with EMR3 and Neoplasm Invasiveness
Pneumonia Antibodies	>1 publications with EMR3 and Pneumonia
Esophageal Neoplasms Antibodies	>1 publications with EMR3 and Esophageal Neoplasms
Atherosclerosis Antibodies	>1 publications with EMR3 and Atherosclerosis
Carcinoma, Squamous Cell Antibodies	>1 publications with EMR3 and Carcinoma, Squamous Cell
Breast Neoplasms Antibodies	>1 publications with EMR3 and Breast Neoplasms

Organs/Tissues associated with anti-EMR3 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>6 publications with EMR3 and Blood
Spleen Antibodies	>1 publications with EMR3 and Spleen
Lung Antibodies	>1 publications with EMR3 and Lung