Mouse Anti-DYNC1I2 Monoclonal Antibody – Cat# MBS211301

DYNEIN Cytoplasmic (DYNC1I2) Antibody – Mouse Monoclonal

Name: DYNC1I2 Antibody; Monoclonal; Mouse; Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS211301
Price: 725 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS211301

reacts with all known forms of the 74 kDa intermediate chain subunit of mammalian cytoplasmic dynein. The antigenic site has been localized to the first 60 amino acids of the N-terminal portion of the molecule. Mouse anti Bovine dynein cytoplasmic 74kDA… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

DYNEIN CYTOPLASMIC (DYNC1I2), Monoclonal Antibody

Full Product Name

MOUSE ANTI BOVINE DYNEIN CYTOPLASMIC 74kDa

Product Gene Name

anti-DYNC1I2 antibody

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

74.1

Host

Mouse

Species Reactivity

Drosophila, Fish, Mouse, Rat, Sheep, Xenopus

Form/Format

Purified
Purified IgG - liquid

Concentration

IgG concentration 1.0 mg/ml (lot specific)

Preparation and Storage

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Molecular Weight

68,377 Da

3D Structure

ModBase 3D Structure for Q0III3

Perservative Stabilisers

0.1% Sodium Azide (NaN3)
Preparation||Purified IgG prepared by affinity chromatography on Protein A

Histology Positive Control Tissue

Cultured MDCK cells, NRR cells, N1E cells and PTK-1 cells.
Buffer Solution||Phosphate buffered saline

Target Species

Bovine

Applications Tested/Suitable for anti-DYNC1I2 antibody

Immunohistology Frozen, Immunoprecipitation (IP), Western Blot (WB)

Application Notes for anti-DYNC1I2 antibody

Immunohistology - Frozen: Minimum Dilution: 1/10; Maximum Dilution: 1/100;
Western Blotting: Minimum Dilution: 1/1000; Maximum Dilution: 1/5000

Other Notes

Small volumes of anti-DYNC1I2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DYNC1I2 purchase

MBS211301 is an antibody targeting DYNC1I2. Also known as MOUSE ANTI BOVINE DYNEIN CYTOPLASMIC 74kDa. Reactive in Drosophila, Fish, Mouse, Rat, Sheep, Xenopus. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for DYNC1I2. It may not necessarily be applicable to this product.

NCBI GI #

115497348

NCBI GeneID

526329

NCBI Accession #

NP_001069351.1

UniProt Primary Accession #

Q0III3

UniProt Related Accession #

Q0III3

GenBank Nucleotide #

NM_001075883.1

NCBI Official Full Name

cytoplasmic dynein 1 intermediate chain 2

NCBI Official Symbol

DYNC1I2

UniProt Protein Name

Cytoplasmic dynein 1 intermediate chain 2

UniProt Synonym Protein Names

Cytoplasmic dynein intermediate chain 2; Dynein intermediate chain 2, cytosolic; DH IC-2

Protein Family

Cytoplasmic dynein

UniProt Gene Name

DYNC1I2

UniProt Synonym Gene Names

DH IC-2

UniProt Entry Name

DC1I2_BOVIN

NCBI Protein Information

cytoplasmic dynein 1 intermediate chain 2; DH IC-2; cytoplasmic dynein intermediate chain 2; dynein intermediate chain 2, cytosolic

UniProt Comments for DYNC1I2

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-DYNC1I2 antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Anchoring Of The Basal Body To The Plasma Membrane Pathway antibodies	Anchoring Of The Basal Body To The Plasma Membrane Pathway Diagram
Assembly Of The Primary Cilium Pathway antibodies	Assembly Of The Primary Cilium Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Centrosome Maturation Pathway antibodies	Centrosome Maturation Pathway Diagram
G2/M Transition Pathway antibodies	G2/M Transition Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Loss Of Nlp From Mitotic Centrosomes Pathway antibodies	Loss Of Nlp From Mitotic Centrosomes Pathway Diagram
Loss Of Proteins Required For Interphase Microtubule Organizationfrom The Centrosome Pathway antibodies	Loss Of Proteins Required For Interphase Microtubule Organizationfrom The Centrosome Pathway Diagram

Organs/Tissues associated with anti-DYNC1I2 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>1 publications with DYNC1I2 and Brain