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Angiotensin I (AGT) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS211459

MBS211459 is an antibody targeting AGT. Also known as MOUSE ANTI HUMAN ANGIOTENSIN I. Reactive in Human. Host: Mouse. More details

$550 / 0.2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ANGIOTENSIN I (AGT), Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN ANGIOTENSIN I
Product Gene Name
Immunogen Sequence
P-F-H-L-V- I-H-N-E-S( -C)
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
BGN/KA/4H
Host
Mouse
Species Reactivity
Human
Form/Format
Purified (Purified IgG - liquid)
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Specificity
ANGIOTENSIN I
This item is specific for Angiotensin I and does not react with angiotensin II, III or angiotensinogen in ELISA.

Angiotensin I is important in the Renin-Angiotensin-Aldosterone System (RAAS). RAAS is responsible for the regulation of blood pressure and water retention in the body.

Angiotensin I is produced from a reaction between the renal enzyme Renin and angiotensinogen. It is converted by Angiotensin Converting Enzyme (ACE) into a vasoactive form called Angiotensin II which is responsible for increasing blood pressure.
Preparation and Storage
Store at +4 degree C or at -20 degree C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of dispatch.
Molecular Weight
53,154 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (230838269..230850336, complement). Location: 1q42.2
OMIM
106150
3D Structure
ModBase 3D Structure for P01019
Immunogen
Synthetic peptide corresponding to amino acids 40-49 of the angiotensinogen precursor (Swiss-Prot entry P01019) conjugated to HMW carrier protein.
Preparation
Purified IgG prepared by affinity chromatography on Protein A
Preservative Stabilizers
0.09% Sodium Azide (NaN3)
Buffer Solution
Phosphate buffered saline
Applications Tested/Suitable for anti-AGT antibody
ELISA (EIA)
Application Notes for anti-AGT antibody
ELISA: In a simple indirect ELISA, using 1.0 ug of Angiotensin I coated per well, the 50% binding was observed at an antibody dilution of 1/12K. Under the same conditions, the end point titre was observed at an antibody dilution of 1/100K.

Other Notes

Small volumes of anti-AGT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AGT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
angiotensinogen preproprotein
NCBI Official Synonym Full Names
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
NCBI Official Symbol
AGT
NCBI Official Synonym Symbols
ANHU; SERPINA8
UniProt Protein Name
Angiotensinogen
UniProt Synonym Protein Names
Serpin A8Cleaved into the following 8 chains:Angiotensin-1; Alternative name(s):; Angiotensin 1-10; Angiotensin I; Ang IAngiotensin-2; Alternative name(s):; Angiotensin 1-8; Angiotensin II; Ang IIAngiotensin-3; Alternative name(s):; Angiotensin 2-8; Angiotensin III; Ang III; Des-Asp[1]-angiotensin IIAngiotensin-4; Alternative name(s):; Angiotensin 3-8; Angiotensin IV
Protein Family
UniProt Gene Name
AGT
UniProt Synonym Gene Names
SERPINA8; Ang I; Ang II; Ang III; Ang IV
UniProt Entry Name
ANGT_HUMAN
NCBI Protein Information
angiotensinogen; serpin A8; angiotensin I; angiotensin II; pre-angiotensinogen; alpha-1 antiproteinase, antitrypsin; serine (or cysteine) proteinase inhibitor

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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