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CD41/CD61 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS211597

MBS211597 is an antibody targeting CD41/CD61. Also known as MOUSE ANTI HUMAN CD41/CD61. Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CD41/CD61, Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN CD41/CD61
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Clone Number
A10-33/1
Host
Mouse
Species Reactivity
Human
Form/Format
Purified (Purified IgG - lyophilised)
Concentration
IgG concentration 0.12 mg/ml after reconstitution. (lot specific)
Specificity
CD41/CD61
Clone A10-33/1 recognizes endothelial cells in various cultures and organs (including lung, liver, gall bladder and skin). It is generally reactive with melanoma, including metastasizing melanomas and in carcinomas. It reacts strongly with purified GPIIb-IIIa which is expressed on platelets but not endothelial cells. Cross reactivity with nervous tissue has also been reported.
Preparation and Storage
Prior to reconstitution store at +4 degree C.
After reconstitution store at +4 degree C or at -20 degree C if preferred.
Storage in frost-free freezers is not recommended. This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.
Molecular Weight
87,058 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (45331208..45390077). Location: 17q21.32
OMIM
173470
3D Structure
ModBase 3D Structure for P05106
Immunogen
Human melanoma cell lines
Reactivity Note
Bovine: Yes
Mouse: Yes
Preparation
Purified IgG prepared by affinity chromatography
Preservative Stabilizers
0.01% Thiomersal
1.0% BSA
Reconstitution
Reconstitute with 0.5ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.
Buffer Solution
Phosphate buffered saline
Applications Tested/Suitable for anti-CD41/CD61 antibody
Immunohistology - Frozen (IHC), Western Blot (WB)
Application Notes for anti-CD41/CD61 antibody
Immunohistology - Frozen: Min Dilution: 1/100
Max Dilution: 1/400
Application Note: The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. We recommends the use of acetone fixation for frozen sections.
Histology Positive Control Tissue: Human Placenta
Immunohistology: The antigen is sensitive to formaldehyde. It is not suitable for use on paraffin embedded sections.

Other Notes

Small volumes of anti-CD41/CD61 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD41/CD61. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
integrin beta-3
NCBI Official Synonym Full Names
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
NCBI Official Symbol
ITGB3
NCBI Official Synonym Symbols
GT; CD61; GP3A; BDPLT2; GPIIIa
UniProt Protein Name
Integrin beta-3
UniProt Synonym Protein Names
Platelet membrane glycoprotein IIIa
UniProt Gene Name
ITGB3
UniProt Synonym Gene Names
GP3A; GPIIIa
UniProt Entry Name
ITB3_HUMAN
NCBI Protein Information
integrin beta-3; platelet membrane glycoprotein IIIa

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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