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Matrix Metalloproteinase 9 (MMP9) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2119629
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MBS2119629 is an antibody targeting MMP9. Also known as APC-Linked Polyclonal Antibody to Matrix Metalloproteinase 9 (MMP9). Reactive in Human, Mouse. Host: Rabbit. More details

$295 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Matrix Metalloproteinase 9 (MMP9), Polyclonal Antibody
Full Product Name
APC-Linked Polyclonal Antibody to Matrix Metalloproteinase 9 (MMP9)
Product Gene Name
anti-MMP9 antibody
Product Synonym Names
GELB; Gelatinase B; CLG4B; CLG4-B; 92 KDa Gelatinase; 92kDa Type IV Collagenase
Immunogen Sequence
Phe108~Ser 508
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
>=100ug/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against MMP9. It has been selected for its ability to recognize MMP9 in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
APC Conjugated Antibody: MMP9 (MBS2119629)
Immunogen: MMP9 (MBS2122652)
Molecular Weight
80,535 Da
3D Structure
ModBase 3D Structure for P41245
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen Sequence
Phe108~Ser508
Cross Reactivity
Mouse
Conjugation
APC

Product Categories/Family for anti-MMP9 antibody

Enzyme & Kinase; Tumor Immunity; Infection Immunity; Cardiovascular Biology; Hepatology
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-MMP9 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Other Notes

Small volumes of anti-MMP9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MMP9. It may not necessarily be applicable to this product.

NCBI GI #
341940960
NCBI GeneID
17395
NCBI Accession #
P41245.2
UniProt Primary Accession #
P41245
UniProt Secondary Accession #
Q06788; Q80XI8; Q9DC02
UniProt Related Accession #
P41245
NCBI Official Full Name
Matrix metalloproteinase-9
NCBI Official Synonym Full Names
matrix metallopeptidase 9
NCBI Official Symbol
Mmp9
NCBI Official Synonym Symbols
Clg4b; MMP-9; B/MMP9; AW743869; pro-MMP-9
UniProt Protein Name
Matrix metalloproteinase-9
UniProt Synonym Protein Names
92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB
Protein Family
Matrix metalloproteinase
UniProt Gene Name
Mmp9
UniProt Synonym Gene Names
Clg4b; MMP-9; GELB
UniProt Entry Name
MMP9_MOUSE
NCBI Protein Information
matrix metalloproteinase-9; GELB; Gel B; gelatinase B; 92kD gelatinase; 92kDa gelatinase; 92 kDa gelatinase; collagenase type IVB; 92kD type IV collagenase; 92kDa type IV collagenase; 92 kDa type IV collagenase; matrix metalloproteinase 9

UniProt Comments for MMP9

MMP9: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with a 25 kDa protein. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1. Activated by 4-aminophenylmercuric acetate and phorbol ester. Up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. Produced by normal alveolar macrophages and granulocytes. Inhibited by histatin-3 1/24 (histatin-5). Inhibited by ECM1. Belongs to the peptidase M10A family.

Protein type: Protease; Secreted; Motility/polarity/chemotaxis; EC 3.4.24.35; Secreted, signal peptide

Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; protein complex; extracellular region

Molecular Function: peptidase activity; identical protein binding; zinc ion binding; hydrolase activity; metallopeptidase activity; fibronectin binding; metal ion binding; metalloendopeptidase activity; endopeptidase activity; protein complex binding

Biological Process: positive regulation of keratinocyte migration; response to drug; ossification; extracellular matrix organization and biogenesis; positive regulation of apoptosis; positive regulation of leukocyte migration; tissue remodeling; positive regulation of synaptic plasticity; proteolysis; protein oligomerization; collagen catabolic process; positive regulation of angiogenesis; negative regulation of fibroblast proliferation; response to oxidative stress; leukocyte migration; skeletal development; embryo implantation; transformation of host cell by virus
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Research Articles on MMP9

1. TNF-alpha-induced MMP-9 expression is mediated through a c-Src-dependent PDGFR transactivation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-MMP9 antibody

 Products by Pathway  Pathway Diagram
 Activation Of Matrix Metalloproteinases Pathway antibodies  Activation Of Matrix Metalloproteinases Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Collagen Degradation Pathway antibodies  Collagen Degradation Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram

Diseases associated with anti-MMP9 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >497 publications with MMP9 and Inflammation
 Neoplasm Invasiveness Antibodies  >403 publications with MMP9 and Neoplasm Invasiveness
 Neoplasm Metastasis Antibodies  >355 publications with MMP9 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >166 publications with MMP9 and Breast Neoplasms
 Liver Diseases Antibodies  >148 publications with MMP9 and Liver Diseases
 Aortic Diseases Antibodies  >98 publications with MMP9 and Aortic Diseases
 Carcinoma, Squamous Cell Antibodies  >96 publications with MMP9 and Carcinoma, Squamous Cell
 Aortic Aneurysm Antibodies  >93 publications with MMP9 and Aortic Aneurysm
 Aortic Aneurysm, Abdominal Antibodies  >76 publications with MMP9 and Aortic Aneurysm, Abdominal
 Carcinoma, Hepatocellular Antibodies  >72 publications with MMP9 and Carcinoma, Hepatocellular

Organs/Tissues associated with anti-MMP9 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >810 publications with MMP9 and Blood
 Lung Antibodies  >356 publications with MMP9 and Lung
 Bone Antibodies  >319 publications with MMP9 and Bone
 Brain Antibodies  >265 publications with MMP9 and Brain
 Liver Antibodies  >211 publications with MMP9 and Liver
 Heart Antibodies  >204 publications with MMP9 and Heart
 Bone Marrow Antibodies  >135 publications with MMP9 and Bone Marrow
 Skin Antibodies  >118 publications with MMP9 and Skin
 Embryonic Tissue Antibodies  >111 publications with MMP9 and Embryonic Tissue
 Eye Antibodies  >85 publications with MMP9 and Eye
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