Mouse Anti-VC1457 Monoclonal Antibody – Cat# MBS211978

CHOLERA TOXIN (VC1457) Antibody – Mouse Monoclonal

Name: VC1457 Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS211978
Price: 550 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS211978

Mouse anti Cholera Toxin alpha antibody, clone 2/166 recognizes the alpha subunit of Cholera toxin.The cholera holotoxin consists of a pentameric ring of Beta subunits whose central pore is occupied by the Alpha subunit. The Alpha subunit contains two chains,… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CHOLERA TOXIN (VC1457), Monoclonal Antibody

Full Product Name

MOUSE ANTI CHOLERA TOXIN ALPHA

Product Gene Name

anti-VC1457 antibody

Clonality

Monoclonal

Isotype

IgM

Clone Number

2/166

Host

Mouse

Form/Format

Purified
Ig fraction - liquid

Concentration

Approximate Protein Concentration: 5.0 mg/ml (lot specific)

Preparation and Storage

Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Molecular Weight

29,336 Da

3D Structure

ModBase 3D Structure for P01555

Perservative Stabilisers

0.09% Sodium Azide (NaN3)
Preparation||Ig fraction prepared by ammonium sulphate precipitation

Immunogen

Vibrio cholerae extract
Buffer Solution||Phosphate buffered saline

Target Species

Bacterial

Applications Tested/Suitable for anti-VC1457 antibody

ELISA (EIA)

Other Notes

Small volumes of anti-VC1457 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VC1457 purchase

MBS211978 is an antibody targeting VC1457. Also known as MOUSE ANTI CHOLERA TOXIN ALPHA. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for VC1457. It may not necessarily be applicable to this product.

NCBI GI #

15641468

NCBI GeneID

2613963

NCBI Accession #

NP_231100.1

UniProt Primary Accession #

P01555

UniProt Secondary Accession #

Q56634; Q9JPV1

UniProt Related Accession #

P01555

GenBank Nucleotide #

NC_002505.1

NCBI Official Full Name

cholera enterotoxin subunit A

NCBI Official Symbol

VC1457

UniProt Protein Name

Cholera enterotoxin subunit A

UniProt Synonym Protein Names

Cholera enterotoxin, A chainCleaved into the following 2 chains:Cholera enterotoxin subunit A1 (EC:2.4.2.-)Alternative name(s):Cholera enterotoxin A1 chain; Cholera enterotoxin alpha chain; NAD(+)--diphthamide ADP-ribosyltransferase

Protein Family

Cholera toxin homolog transcriptional activator

UniProt Gene Name

ctxA

UniProt Synonym Gene Names

toxA

UniProt Entry Name

CHTA_VIBCH

NCBI Protein Information

cholera enterotoxin subunit A

UniProt Comments for VC1457

The A1 chain catalyzes the ADP-ribosylation of Gs alpha, a GTP-binding regulatory protein, to activate the adenylate cyclase. This leads to an overproduction of cAMP and eventually to a hypersecretion of chloride and bicarbonate followed by water, resulting in the characteristic cholera stool. The A2 chain tethers A1 to the pentameric ring.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.