• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Sarcolipin (SLN) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2120155
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2120155 is an antibody targeting SLN. Also known as APC-Linked Polyclonal Antibody to Sarcolipin (SLN). Reactive in Human. Host: Rabbit. More details

$330 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Sarcolipin (SLN), Polyclonal Antibody
Full Product Name
APC-Linked Polyclonal Antibody to Sarcolipin (SLN)
Product Gene Name
anti-SLN antibody
Immunogen Sequence
Met1~Tyr31
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
>=100ug/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against SLN. It has been selected for its ability to recognize SLN in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: SLN (MBS2112251)
APC Conjugated Antibody: SLN (MBS2120155)
Matching Pairs
APC Conjugated Antibody: SLN (MBS2120155)
Immunogen: SLN (MBS2123021)
OMIM
602203
3D Structure
ModBase 3D Structure for O00631
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen Sequence
Met1~Tyr31
Cross Reactivity
Human
Conjugation
APC

Product Categories/Family for anti-SLN antibody

Signal Transduction
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-SLN antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Other Notes

Small volumes of anti-SLN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLN. It may not necessarily be applicable to this product.

NCBI GI #
2811004
NCBI GeneID
6588
NCBI Accession #
O00631.1
UniProt Primary Accession #
O00631
UniProt Secondary Accession #
Q6ICV3
UniProt Related Accession #
O00631
NCBI Official Full Name
Sarcolipin
NCBI Official Synonym Full Names
sarcolipin
NCBI Official Symbol
SLN
UniProt Protein Name
Sarcolipin
Protein Family
Sarcolipin
UniProt Gene Name
SLN
UniProt Entry Name
SARCO_HUMAN
NCBI Protein Information
sarcolipin

NCBI Summary for SLN

Sarcoplasmic reticulum Ca(2+)-ATPases are transmembrane proteins that catalyze the ATP-dependent transport of Ca(2+) from the cytosol into the lumen of the sarcoplasmic reticulum in muscle cells. This gene encodes a small proteolipid that regulates several sarcoplasmic reticulum Ca(2+)-ATPases. The transmembrane protein interacts with Ca(2+)-ATPases and reduces the accumulation of Ca(2+) in the sarcoplasmic reticulum without affecting the rate of ATP hydrolysis. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for SLN

sarcolipin: Sarcoplasmic reticulum Ca(2+)-ATPases are transmembrane proteins that catalyze the ATP-dependent transport of Ca(2+) from the cytosol into the lumen of the sarcoplasmic reticulum in muscle cells. This gene encodes a small proteolipid that regulates several sarcoplasmic reticulum Ca(2+)-ATPases. The transmembrane protein interacts with Ca(2+)-ATPases and reduces the accumulation of Ca(2+) in the sarcoplasmic reticulum without affecting the rate of ATP hydrolysis. [provided by RefSeq, Jul 2008]

Protein type: Endoplasmic reticulum; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q22.3

Cellular Component: sarcoplasmic reticulum membrane; sarcoplasmic reticulum; integral to membrane

Molecular Function: enzyme inhibitor activity; ATPase binding

Biological Process: calcium ion transport; negative regulation of catalytic activity; regulation of calcium ion transport; negative regulation of protein complex disassembly
Show more

Research Articles on SLN

1. SLN and PLN are co-expressed in most fibers, which suggests that super-inhibition of SERCAs may be physiologically important in the regulation of intracellular Ca2+ in human skeletal muscle.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLN antibody

 Reference Product  PubMed Publications
 ATP2A2 antibody  >45 publications with SLN and ATP2A2
 PLN antibody  >23 publications with SLN and PLN
 ATP2A1 antibody  >3 publications with SLN and ATP2A1

Diseases associated with anti-SLN antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1307 publications with SLN and Breast Neoplasms
 Carcinoma Antibodies  >861 publications with SLN and Carcinoma
 Adenocarcinoma Antibodies  >411 publications with SLN and Adenocarcinoma
 Uterine Cervical Neoplasms Antibodies  >99 publications with SLN and Uterine Cervical Neoplasms
 Neoplasms, Experimental Antibodies  >70 publications with SLN and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >41 publications with SLN and Lung Neoplasms
 Cardiovascular Diseases Antibodies  >34 publications with SLN and Cardiovascular Diseases
 Mammary Neoplasms, Animal Antibodies  >33 publications with SLN and Mammary Neoplasms, Animal
 Prostatic Neoplasms Antibodies  >29 publications with SLN and Prostatic Neoplasms
 Necrosis Antibodies  >25 publications with SLN and Necrosis

Organs/Tissues associated with anti-SLN antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >297 publications with SLN and Nerve
 Muscle Antibodies  >189 publications with SLN and Muscle
 Brain Antibodies  >169 publications with SLN and Brain
 Liver Antibodies  >83 publications with SLN and Liver
 Heart Antibodies  >72 publications with SLN and Heart
 Mouth Antibodies  >68 publications with SLN and Mouth
 Thyroid Antibodies  >68 publications with SLN and Thyroid
 Prostate Antibodies  >43 publications with SLN and Prostate
 Eye Antibodies  >43 publications with SLN and Eye
 Intestine Antibodies  >31 publications with SLN and Intestine
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000