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Il-6 (IL6) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS212254

Mouse anti Sheep Interleukin-6 antibody, clone 4B6 recognizes ovine interleukin-6 (IL-6) and has also been reported to recognise recombinant human IL-6 and bovine IL-6 transfected cells.Mouse anti Sheep Interleukin-6 antibody, clone 4B6 does not cross react… More details

$695 / 0.25 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-6 (IL6), Monoclonal Antibody
Full Product Name
MOUSE ANTI SHEEP INTERLEUKIN-6
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4B6
Host
Mouse
Species Reactivity
Reacts with: Monkey
N.B. Antibody reactivity and working conditions may vary between species.
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
23,446 Da
3D Structure
ModBase 3D Structure for P29455
Perservative Stabilisers
0.1% Sodium Azide
Buffer Solution
Phosphate buffered saline
Target Species
Sheep
Immunogen
Recombinant ovine IL-6
Applications Tested/Suitable for anti-IL6 antibody
ELISA (EIA), Flow cytometry (FC/FACS)*, Western Blot (WB)
Application Notes for anti-IL6 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
ELISA: Maximum Dilution: 5ug/ml (as a coating antibody)
Flow Cytometry: Application Note: Membrane permeabilization is required for this application. MyBioSource recommend the use of Leucoperm for this purpose.

Other Notes

Small volumes of anti-IL6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL6 purchase

MBS212254 is an antibody targeting IL6. Also known as MOUSE ANTI SHEEP INTERLEUKIN-6. Reactive in Reacts with: Monkey
N.B. Antibody reactivity and working conditions may vary between species.. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IL6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-6
NCBI Official Symbol
IL6
UniProt Protein Name
Interleukin-6
Protein Family
UniProt Gene Name
IL6
UniProt Synonym Gene Names
IL-6
UniProt Entry Name
IL6_SHEEP
NCBI Protein Information
interleukin-6; IL-6

UniProt Comments for IL6

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-IL6 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >416 publications with IL6 and Bone
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