• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CD89 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS212330

Mouse anti Human CD89 antibody, clone MIP8a recognizes the human CD89 cell surface antigen, a 50-75kDa cell surface glycoprotein that is also known as the IgA receptor (Fc alpha R). CD89 is expressed by peripheral blood monocytes and neutrophils. MIP8a blocks… More details

$580 / 0.2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD89, Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN CD89
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Clone Number
MIP8a
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
28,343 Da
OMIM
147045
3D Structure
ModBase 3D Structure for P24071
Perservative Stabilisers
0.09% Sodium Azide
Immunogen
Recombinant soluble human Fc alpha R
Buffer Solution||Phosphate buffered saline
Target Species
Human
Applications Tested/Suitable for anti-CD89 antibody
ELISA (EIA), Flow cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-CD89 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood
Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/100

Testing Data of anti-CD89 antibody

Staining of human peripheral blood granulocytes with Mouse anti Human CD89: RPE (MBS213674)
Mouse Anti-CD89 Monoclonal Antibody – Cat# MBS212330

Testing Data of anti-CD89 antibody

Staining of human peripheral blood granulocytes with Mouse anti Human CD89:Low endotoxin (MBS224611)
Mouse Anti-CD89 Monoclonal Antibody, Testing Data – Cat# MBS212330

Other Notes

Small volumes of anti-CD89 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD89 purchase

MBS212330 is an antibody targeting CD89. Also known as MOUSE ANTI HUMAN CD89. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD89. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
immunoglobulin alpha Fc receptor isoform a
NCBI Official Synonym Full Names
Fc fragment of IgA, receptor for
NCBI Official Symbol
FCAR
NCBI Official Synonym Symbols
CD89; FcalphaRI
UniProt Protein Name
Immunoglobulin alpha Fc receptor
UniProt Synonym Protein Names
CD_antigen: CD89
UniProt Gene Name
FCAR
UniProt Synonym Gene Names
CD89; IgA Fc receptor
UniProt Entry Name
FCAR_HUMAN
NCBI Protein Information
immunoglobulin alpha Fc receptor; Fc alpha receptor

NCBI Summary for CD89

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for CD89

FCAR: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. 11 isoforms of the human protein are produced by alternative splicing.

Protein type: Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: integral to plasma membrane; plasma membrane; extracellular region

Molecular Function: IgA binding

Biological Process: immune response
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000