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CD236 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS212433

Mouse anti Human CD236 antibody, clone BRIC10 recognizes an epitope in the N-terminal region of CD236, also known as glycophorin C (GPC). CD236 is an integral membrane protein which carries the Gerbich blood group antigens. Expression of CD236 is not… More details

$580 / 0.2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CD236, Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN CD236
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Clone Number
BRIC10
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
11,910 Da
OMIM
110750
3D Structure
ModBase 3D Structure for P04921
Perservative Stabilisers
0.09% Sodium Azide
Preparation||Purified IgG prepared by affinity chromatography on Protein G.
Immunogen
Human erythrocytes
Buffer Solution||TRIS buffered glycine
Target Species
Human
Applications Tested/Suitable for anti-CD236 antibody
Flow cytometry (FC/FACS), Western Blot (WB)
Application Notes for anti-CD236 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.

Other Notes

Small volumes of anti-CD236 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD236 purchase

MBS212433 is an antibody targeting CD236. Also known as MOUSE ANTI HUMAN CD236. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD236. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
glycophorin-C isoform 3
NCBI Official Synonym Full Names
glycophorin C (Gerbich blood group)
NCBI Official Symbol
GYPC
NCBI Official Synonym Symbols
GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2'
UniProt Protein Name
Glycophorin-C
UniProt Synonym Protein Names
Glycoconnectin; Glycophorin-D; GPD; Glycoprotein beta; PAS-2'; Sialoglycoprotein D; CD_antigen: CD236
Protein Family
UniProt Gene Name
GYPC
UniProt Synonym Gene Names
GLPC; GPC; GPD
UniProt Entry Name
GLPC_HUMAN
NCBI Protein Information
glycophorin-C; glycoconnectin; glycophorin-D; glycoprotein beta; sialoglycoprotein D

NCBI Summary for CD236

Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
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UniProt Comments for CD236

GYPC: This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells. Belongs to the glycophorin-C family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q14-q21

Cellular Component: cortical cytoskeleton; membrane; integral to plasma membrane; plasma membrane

Molecular Function: protein binding

Disease: Malaria, Susceptibility To; Blood Group, Gerbich System
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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