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BLTR Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS212498

Mouse anti Human BLTR antibody, clone 202/7B1 recognizes the human BLTR molecule, the leukotriene B4 receptor. BLTR is expressed by peripheral blood granulocytes and is important in the pro-inflammatory response. More details

$440 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BLTR, Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN BLTR
Product Gene Name
anti-BLTR antibody
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
202/7B1
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
37,557 Da
OMIM
601531
3D Structure
ModBase 3D Structure for Q15722
Perservative Stabilisers
0.09% Sodium Azide
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Target Species
Human
Applications Tested/Suitable for anti-BLTR antibody
Immunohistology Frozen, Flow cytometry (FC/FACS), Immunofluorescence (IF), Immunoassay (IY)
Application Notes for anti-BLTR antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood.
Flow Cytometry: Minimum Dilution: 1/100; Maximum Dilution: 1/200

Testing Data of anti-BLTR antibody

Staining of human peripheral blood granulocytes with Mouse anti Human BLTR:Alexa Fluor 647 (MBS212497A647)
Mouse Anti-BLTR Monoclonal Antibody – Cat# MBS212498

Testing Data of anti-BLTR antibody

Staining of human peripheral blood monocytes with Mouse anti Human BLTR
Mouse Anti-BLTR Monoclonal Antibody, Testing Data – Cat# MBS212498

Testing Data of anti-BLTR antibody

Staining of human peripheral blood granulocytes with Mouse anti Human BLTR:FITC (MBS210842)
Mouse Anti-BLTR Monoclonal Antibody, Testing Data – Cat# MBS212498

Testing Data of anti-BLTR antibody

Staining of human peripheral blood monocytes with Mouse anti Human BLTR: Azide Free (MBS210209)
Mouse Anti-BLTR Monoclonal Antibody, Testing Data – Cat# MBS212498

Testing Data of anti-BLTR antibody

Staining of human peripheral blood granulocytes with Mouse anti Human BLTR:RPE (MBS213723)
Mouse Anti-BLTR Monoclonal Antibody, Testing Data – Cat# MBS212498

Other Notes

Small volumes of anti-BLTR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BLTR purchase

MBS212498 is an antibody targeting BLTR. Also known as MOUSE ANTI HUMAN BLTR. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for BLTR. It may not necessarily be applicable to this product.

NCBI GI #
221218998
NCBI GeneID
1241
NCBI Accession #
NP_001137391.1
UniProt Primary Accession #
Q15722
UniProt Secondary Accession #
Q13305; Q53XV5; Q92641; Q9BSU5
UniProt Related Accession #
Q15722
GenBank Nucleotide #
NM_001143919.2
NCBI Official Full Name
leukotriene B4 receptor 1
NCBI Official Synonym Full Names
leukotriene B4 receptor
NCBI Official Symbol
LTB4R
NCBI Official Synonym Symbols
BLT1; BLTR; P2Y7; GPR16; LTBR1; P2RY7; CMKRL1; LTB4R1
UniProt Protein Name
Leukotriene B4 receptor 1
UniProt Synonym Protein Names
Chemoattractant receptor-like 1; G-protein coupled receptor 16; P2Y purinoceptor 7; P2Y7
Protein Family
Multidrug-efflux transporter 2 regulator
UniProt Gene Name
LTB4R
UniProt Synonym Gene Names
BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7; LTB4-R 1; LTB4-R1; P2Y7
UniProt Entry Name
LT4R1_HUMAN
NCBI Protein Information
leukotriene B4 receptor 1; G protein-coupled receptor 16; G-protein coupled receptor 16; LTB4-R 1; LTB4-R1; P2Y purinoceptor 7; chemoattractant receptor-like 1; chemokine receptor-like 1; purinergic receptor P2Y, G-protein coupled, 7

UniProt Comments for BLTR

LTB4R: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q11.2-q12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: leukotriene B4 receptor activity; nucleotide binding; leukotriene receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; muscle contraction; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; cell motility; inflammatory response
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Research Articles on BLTR

1. Results suggest that NOX2-derived ROS-mediated BLT1 trafficking to the cell surface plays a key role in the exocytosis of human eosinophils induced by LTB4.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BLTR antibody

 Reference Product  PubMed Publications
 CYSLTR2 antibody  >1 publications with BLTR and CYSLTR2
 ADRBK1 antibody  >1 publications with BLTR and ADRBK1
 CCK antibody  >1 publications with BLTR and CCK

Pathways associated with anti-BLTR antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Eicosanoid Ligand-binding Receptors Pathway antibodies  Eicosanoid Ligand-binding Receptors Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Leukotriene Receptors Pathway antibodies  Leukotriene Receptors Pathway Diagram

Diseases associated with anti-BLTR antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >35 publications with BLTR and Inflammation
 Asthma Antibodies  >16 publications with BLTR and Asthma
 Necrosis Antibodies  >8 publications with BLTR and Necrosis
 Pancreatic Neoplasms Antibodies  >2 publications with BLTR and Pancreatic Neoplasms
 Leukemia, Myeloid Antibodies  >2 publications with BLTR and Leukemia, Myeloid
 Disease Models, Animal Antibodies  >2 publications with BLTR and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >2 publications with BLTR and Neoplasms, Experimental
 Fibrosis Antibodies  >2 publications with BLTR and Fibrosis
 Bronchial Hyperreactivity Antibodies  >1 publications with BLTR and Bronchial Hyperreactivity
 Lung Neoplasms Antibodies  >1 publications with BLTR and Lung Neoplasms

Organs/Tissues associated with anti-BLTR antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >48 publications with BLTR and Blood
 Lung Antibodies  >14 publications with BLTR and Lung
 Skin Antibodies  >5 publications with BLTR and Skin
 Bone Marrow Antibodies  >5 publications with BLTR and Bone Marrow
 Kidney Antibodies  >3 publications with BLTR and Kidney
 Spleen Antibodies  >2 publications with BLTR and Spleen
 Uterus Antibodies  >2 publications with BLTR and Uterus
 Eye Antibodies  >1 publications with BLTR and Eye
 Ovary Antibodies  >1 publications with BLTR and Ovary
 Brain Antibodies  >1 publications with BLTR and Brain
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