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Glycogen Phosphorylase, Muscle (PYGM) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2126830

MBS2126830 is an antibody targeting PYGM. Also known as Anti-Glycogen Phosphorylase, Muscle (PYGM) Polyclonal Antibody. Reactive in Mouse. Host: Rabbit. More details

$155 / 25 Tests +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glycogen Phosphorylase, Muscle (PYGM), Polyclonal Antibody
Full Product Name
Anti-Glycogen Phosphorylase, Muscle (PYGM) Polyclonal Antibody
Product Gene Name
anti-PYGM antibody
Product Synonym Names
PYGM/Glycogen Phosphorylase, Muscle; GPMM; Phosphorylase,Glycogen; McArdle Syndrome,Glycogen Storage Disease Type V; Myophosphorylase
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Liquid; 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
0.5mg/mL (Please refer to the vial label for the specific concentration.) (lot specific)
Preparation and Storage
Store at 2 degree C to 8 degree C for frequent use, -20 degree C for 12 months
Molecular Weight
97,286 Da
3D Structure
ModBase 3D Structure for Q9WUB3
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
Recombinant proteins/RP
Sequence of Immunogen
Arg11~Gly187 (Accession # Q9WUB3), with N-terminal His Tag
Organism Species
Mus musculus (Mouse)
Features
Flow-cytometry antibodies/FA

Product Categories/Family for anti-PYGM antibody

Enzyme & Kinase; Metabolic pathway; Endocrinology; Primary
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PYGM antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-PYGM antibody
For flow cytometry, the suggested use of this reagent is 1-5ul per 10^6 cells in 100ul volume.

Other Notes

Small volumes of anti-PYGM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PYGM. It may not necessarily be applicable to this product.

NCBI GI #
6755256
NCBI GeneID
19309
NCBI Accession #
NP_035354
UniProt Primary Accession #
Q9WUB3
UniProt Related Accession #
Q9WUB3
GenBank Nucleotide #
NM_011224.1
NCBI Official Full Name
glycogen phosphorylase, muscle form
NCBI Official Synonym Full Names
muscle glycogen phosphorylase
NCBI Official Symbol
Pygm
NCBI Official Synonym Symbols
PG; AI115133
UniProt Protein Name
Glycogen phosphorylase, muscle form
UniProt Synonym Protein Names
Myophosphorylase
Protein Family
Glycogen phosphorylase
UniProt Gene Name
Pygm
UniProt Entry Name
PYGM_MOUSE
NCBI Protein Information
glycogen phosphorylase, muscle form

UniProt Comments for PYGM

PYGM: an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. Dimers associate into a tetramer to form the enzymatically active phosphorylase A. Phosphorylation of Ser-14 converts phosphorylase B (unphosphorylated) to phosphorylase A.

Protein type: Phosphorylase; Transferase; Endoplasmic reticulum; Carbohydrate Metabolism - starch and sucrose; EC 2.4.1.1

Cellular Component: sarcoplasmic reticulum; cytoplasm; Z disc

Molecular Function: transferase activity; transferase activity, transferring glycosyl groups; glycogen phosphorylase activity; phosphorylase activity; nucleotide binding; drug binding; carbohydrate binding; catalytic activity; pyridoxal phosphate binding; AMP binding

Biological Process: cellular calcium ion homeostasis; glycogen metabolic process; response to organic substance; response to cAMP; glycogen catabolic process; metabolic process; carbohydrate metabolic process; response to hypoxia
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Research Articles on PYGM

1. Data suggest that the irreversible inhibition of glycogen phosphorylase (GP) could represent one of the mechanisms that contribute to mercury-dependent muscle toxicity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PYGM antibody

 Reference Product  PubMed Publications
 Gys1 antibody  >5 publications with PYGM and Gys1
 Phkb antibody  >3 publications with PYGM and Phkb
 Agl antibody  >2 publications with PYGM and Agl
 Gbe1 antibody  >2 publications with PYGM and Gbe1
 Phkg1 antibody  >1 publications with PYGM and Phkg1
 Gys2 antibody  >1 publications with PYGM and Gys2
 Pgm2 antibody  >1 publications with PYGM and Pgm2

Pathways associated with anti-PYGM antibody

 Products by Pathway  Pathway Diagram
 Glucagon Signaling Pathway antibodies  Glucagon Signaling Pathway Diagram
 Glucagon Signaling Pathway antibodies  Glucagon Signaling Pathway Diagram
 Glucose Metabolism Pathway antibodies  Glucose Metabolism Pathway Diagram
 Glycogen Metabolism Pathway antibodies  Glycogen Metabolism Pathway Diagram
 Glycogen Breakdown (glycogenolysis) Pathway antibodies  Glycogen Breakdown (glycogenolysis) Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram

Diseases associated with anti-PYGM antibody

 Disease Name  Pubmed Publications
 Glycogen Storage Disease Type V Antibodies  >59 publications with PYGM and Glycogen Storage Disease Type V
 Adenocarcinoma Antibodies  >15 publications with PYGM and Adenocarcinoma
 Hyperplasia Antibodies  >10 publications with PYGM and Hyperplasia
 Muscular Diseases Antibodies  >9 publications with PYGM and Muscular Diseases
 Lung Neoplasms Antibodies  >7 publications with PYGM and Lung Neoplasms
 Breast Neoplasms Antibodies  >6 publications with PYGM and Breast Neoplasms
 Liver Diseases Antibodies  >2 publications with PYGM and Liver Diseases
 Cardiovascular Diseases Antibodies  >2 publications with PYGM and Cardiovascular Diseases
 Diabetes Mellitus Antibodies  >2 publications with PYGM and Diabetes Mellitus
 Skin Neoplasms Antibodies  >2 publications with PYGM and Skin Neoplasms

Organs/Tissues associated with anti-PYGM antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >93 publications with PYGM and Muscle
 Liver Antibodies  >9 publications with PYGM and Liver
 Lung Antibodies  >8 publications with PYGM and Lung
 Brain Antibodies  >5 publications with PYGM and Brain
 Heart Antibodies  >5 publications with PYGM and Heart
 Skin Antibodies  >4 publications with PYGM and Skin
 Eye Antibodies  >4 publications with PYGM and Eye
 Stomach Antibodies  >2 publications with PYGM and Stomach
 Bone Antibodies  >1 publications with PYGM and Bone
 Spinal Cord Antibodies  >1 publications with PYGM and Spinal Cord
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