IFN ALPHA (IFNA3) Antibody – Mouse Monoclonal

Monoclonal

IgG1

UMCh3-IFNa

Mouse

Purified
Purified IgG - liquid

IgG concentration 0.5 mg/ml (lot specific)

This item recognizes chicken Interferon alpha (chIFN-alpha).
The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken.
A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.
This item does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha.

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

22,116 Da

ModBase 3D Structure for P42165

0.09% Sodium Azide
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Recombinant chicken Interferon alpha.
Buffer Solution||Phosphate buffered saline

Chicken