Immunodeficiency VIRUS Gp95 (FELINE) Antibody – Mouse Monoclonal

Mouse anti Feline Immunodeficiency Virus gp95 antibody, clone SU1-30 recognizes the relatively conserved E60 peptide (amino acid sequence SSWKQRNRWEWRPDF) located within the V3 region of FIV (Feline Immunodeficiency Virus) envelope glycoprotein SU,gp95. The primary receptor for FIV infection of cats has been identified as the T-cell activation antigen CD134 which, along with CXC chemokine receptor 4 (CXCR4), facilitates the infection of CD4+ primary target cells, resulting in a depletion in the CD4+ population. Studies have shown that the V3 loop of SU,gp95 is a major immunogenic domain, suggested to contain the main determinants for the binding of FIV SU,gp95 to CXCR4 (Sundstrom, M. et al. 2008). Mouse anti Feline Immunodeficiency Virus gp95 antibody, clone SU1-30 has been shown to inhibit the sCD134-activated entry of both clade B and clade C FIV strains (de Parseval, A. et al. 2006). Mouse anti Feline Immunodeficiency Virus gp95 antibody, clone SU1-30 does not recognise Feline Leukaemia Virus, Feline Herpes Virus type 1, Feline Coronavirus or Feline Calicivirus. Removal of Sodium Azide is recommended prior to use in functional studies - MyBioSource recommend the use of EQU003 for this purpose.

Small volumes of anti-FELINE IMMUNODEFICIENCY VIRUS gp95 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS212874 is an antibody targeting FELINE IMMUNODEFICIENCY VIRUS gp95. Also known as MOUSE ANTI FELINE IMMUNODEFICIENCY VIRUS gp95. Host: Mouse.