Mouse Anti-IgA Monoclonal Antibody – Cat# MBS213033

Sandwich ELISA analysis of human IgA binding using Mouse anti Human IgA as a capture reagent and biotinylated Mouse anti Human IgA (MBS211704) as a detection reagent with purified human IgA (MBS230288) as antigen. Subsequent detection is by HRP conjugated streptavidin and substrate. Microtitre plate is read at O.D. 450 nm on the iMark Microplate Absorbance Reader . Serum sample is displayed at 25000 (Blue) and 50000 (Red) fold dilutions

IgA Antibody – Mouse Monoclonal

Name: IgA Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS213033
Price: 565 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS213033

MBS213033 recognises human immunoglobulin alpha heavy chains. No cross reactivity observed with IgG, IgM or free kappa and lambda light chains. More details

$565 / 0.2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IgA, Monoclonal Antibody

Full Product Name

MOUSE ANTI HUMAN IgA HEAVY CHAIN

Product Gene Name

anti-IgA antibody

Clonality

Monoclonal

Isotype

IgG1

Clone Number

Mc24-2E11

Host

Mouse

Form/Format

Purified
Purified IgG - liquid

Concentration

IgG concentration 1 mg/ml (lot specific)

Specificity

This item recognises human immunoglobulin alpha heavy chains. No cross reactivity observed with IgG, IgM or free kappa and lambda light chains.

Preparation and Storage

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Molecular Weight

37,655 Da

OMIM

146900

Perservative Stabilisers

0.09% Sodium Azide
Preparation||Purified IgG prepared by affinity chromatography on Protein G

Immunogen

Reduced and alkylated human IgA
Fusion Partners||Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Buffer Solution||Phosphate buffered saline

Target Species

Human

Applications Tested/Suitable for anti-IgA antibody

Immunohistology Frozen, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)

Other Notes

Small volumes of anti-IgA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IgA purchase

MBS213033 is an antibody targeting IgA. Also known as MOUSE ANTI HUMAN IgA HEAVY CHAIN. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IgA. It may not necessarily be applicable to this product.

NCBI GI #

113584

NCBI GeneID

3493

NCBI Accession #

P01876.2

UniProt Related Accession #

P01876

NCBI Official Full Name

Ig alpha-1 chain C region, partial

NCBI Official Synonym Full Names

immunoglobulin heavy constant alpha 1

NCBI Official Symbol

IGHA1

NCBI Official Synonym Symbols

IgA1

UniProt Protein Name

Ig alpha-1 chain C region

Protein Family

IgA-specific serine endopeptidase autotransporter

UniProt Gene Name

IGHA1

UniProt Entry Name

IGHA1_HUMAN

UniProt Comments for IgA

IGHA1: Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.

Protein type: Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: extracellular space; extracellular region

Molecular Function: antigen binding

Biological Process: receptor-mediated endocytosis; retinal homeostasis; glomerular filtration; antibacterial humoral response; immune response; protein-chromophore linkage

Research Articles on IgA

1. The heritability of IgA levels is moderate and can partly be attributable to common variation in the CD30L locus.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IgA antibody

Products by Pathway	Pathway Diagram
Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies	Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
Inflammatory Response Pathway antibodies	Inflammatory Response Pathway Diagram
Regulation Of Nuclear SMAD2/3 Signaling Pathway antibodies	Regulation Of Nuclear SMAD2/3 Signaling Pathway Diagram
Scavenging Of Heme From Plasma Pathway antibodies	Scavenging Of Heme From Plasma Pathway Diagram

Organs/Tissues associated with anti-IgA antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with IgA and Blood
Brain Antibodies	>1 publications with IgA and Brain