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CD8 BETA Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS213209

Mouse anti Rat CD8 beta antibody, clone 341 recognizes the beta chain of the rat CD8 cell surface antigen, expressed on thymocytes and peripheral cytotoxic/suppressor cells. CD8b is not expressed by NK cells or by intestinal intraepithelial T cells. Mouse… More details

$440 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CD8 BETA, Monoclonal Antibody
Full Product Name
MOUSE ANTI RAT CD8 BETA
Product Gene Name
anti-CD8 BETA antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
341
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for one month or at -20 degree C for longer. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
23,400 Da
3D Structure
ModBase 3D Structure for P05541
Perservative Stabilisers
0.09% Sodium Azide
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen
Rat/mouse T cell hybrids expressing CD8
Fusion Partners||Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63Ag8.653 myeloma cell line.
Buffer Solution||Phosphate buffered saline
Target Species
Rat
Applications Tested/Suitable for anti-CD8 BETA antibody
Flow cytometry (FC/FACS), Immunoprecipitation (IP)
Application Notes for anti-CD8 BETA antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: 1/100; Maximum Dilution: 1/200

Testing Data of anti-CD8 BETA antibody

Immunofluorescesence staining of rat lymph node cryosection with Mouse anti Rat CD8beta, clone 341 , red in A and Mouse anti Rat anti Mouse CD4 antibody, clone W3/25 , green in B. C is the merged picture C with nuclei counterstained blue using DAPI. Medium power
Mouse Anti-CD8 BETA Monoclonal Antibody – Cat# MBS213209

Testing Data of anti-CD8 BETA antibody

Immunoperoxidase staining of rat lymph node cryosection with Mouse anti Rat CD8beta antibody, clone 341 followed by horseradish peroxidase conjugated Goat anti Mouse IgG1 (MBS235406) as a detection reagent. Low power
Mouse Anti-CD8 BETA Monoclonal Antibody, Testing Data – Cat# MBS213209

Testing Data of anti-CD8 BETA antibody

Rat splenocytes stained with Mouse anti Rat CD8 Beta:FITC (MBS211124)
Mouse Anti-CD8 BETA Monoclonal Antibody, Testing Data – Cat# MBS213209

Testing Data of anti-CD8 BETA antibody

Immunofluorescesence staining of rat lymph node cryosection with Mouse anti Rat CD8beta, clone 341 , red in A and Mouse anti Rat anti Mouse CD4 antibody, clone W3/25 , green in B. C is the merged picture C with nuclei counterstained blue using DAPI. High power
Mouse Anti-CD8 BETA Monoclonal Antibody, Testing Data – Cat# MBS213209

Testing Data of anti-CD8 BETA antibody

Immunoperoxidase staining of rat lymph node cryosection with Mouse anti Rat CD8beta antibody, clone 341 followed by horseradish peroxidase conjugated Goat anti Mouse IgG1 (MBS235406) as a detection reagent. Medium power
Mouse Anti-CD8 BETA Monoclonal Antibody, Testing Data – Cat# MBS213209

Testing Data of anti-CD8 BETA antibody

Immunoperoxidase staining of rat lymph node cryosection with Mouse anti Rat CD8beta antibody, clone 341 followed by horseradish peroxidase conjugated Goat anti Mouse IgG1 (MBS235406) as a detection reagent. High power
Mouse Anti-CD8 BETA Monoclonal Antibody, Testing Data – Cat# MBS213209

Testing Data of anti-CD8 BETA antibody

Immunofluorescesence staining of rat lymph node cryosection with Mouse anti Rat CD8beta, clone 341 , red in A and Mouse anti Rat anti Mouse CD4 antibody, clone W3/25 , green in B. C is the merged picture C with nuclei counterstained blue using DAPI. Low power
Mouse Anti-CD8 BETA Monoclonal Antibody, Testing Data – Cat# MBS213209

Other Notes

Small volumes of anti-CD8 BETA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD8 BETA purchase

MBS213209 is an antibody targeting CD8 BETA. Also known as MOUSE ANTI RAT CD8 BETA. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD8 BETA. It may not necessarily be applicable to this product.

NCBI GI #
13928728
NCBI GeneID
24931
NCBI Accession #
NP_113727.1
UniProt Primary Accession #
P05541
UniProt Related Accession #
P05541
GenBank Nucleotide #
NM_031539.1
NCBI Official Full Name
T-cell surface glycoprotein CD8 beta chain
NCBI Official Synonym Full Names
CD8b molecule
NCBI Official Symbol
Cd8b
NCBI Official Synonym Symbols
Cd8b1
UniProt Protein Name
T-cell surface glycoprotein CD8 beta chain
UniProt Synonym Protein Names
CD8 antigen 37 kDa chain; OX-8 membrane antigen; CD_antigen: CD8b
Protein Family
Putative T-cell surface glycoprotein
UniProt Gene Name
Cd8b
UniProt Synonym Gene Names
Cd8b1
UniProt Entry Name
CD8B_RAT
NCBI Protein Information
T-cell surface glycoprotein CD8 beta chain; CD8 antigen 37 kDa chain; CD8 antigen beta-chain; CD8 antigen, beta chain; CD8 antigen, beta-chain; OX-8 membrane antigen

NCBI Summary for CD8 BETA

a marker for cytotoxic T cells; involved in cell-cell interactions [RGD, Feb 2006]

UniProt Comments for CD8 BETA

Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.

Research Articles on CD8 BETA

1. CD8 positive T suppressor cells protect allogenic recipients from acute rejection in rats liver transplantation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD8 BETA antibody

 Reference Product  PubMed Publications
 Cd8a antibody  >21 publications with CD8 BETA and Cd8a
 Cd4 antibody  >17 publications with CD8 BETA and Cd4
 Lck antibody  >1 publications with CD8 BETA and Lck

Pathways associated with anti-CD8 BETA antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
 Primary Immunodeficiency Pathway antibodies  Primary Immunodeficiency Pathway Diagram

Diseases associated with anti-CD8 BETA antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >2 publications with CD8 BETA and Disease Models, Animal
 Death Antibodies  >1 publications with CD8 BETA and Death
 Necrosis Antibodies  >1 publications with CD8 BETA and Necrosis
 Sepsis Antibodies  >1 publications with CD8 BETA and Sepsis
 Liver Diseases Antibodies  >1 publications with CD8 BETA and Liver Diseases

Organs/Tissues associated with anti-CD8 BETA antibody

 Organ/Tissue Name  Pubmed Publications
 Thymus Antibodies  >6 publications with CD8 BETA and Thymus
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