CD326 Antibody – Mouse Monoclonal

Monoclonal

IgG1

HEA-125

Mouse

Human

Ready To Use (Purified IgG - liquid, ready to use.)

CD326
This antibody recognises the 34kD cell surface antigen known as CD326 or Epithelial Cell Adhesion Molecule (Ep-CAM). This antigen has been identified independently by a number of groups, and it has been known by a variety of names including Epithelial Specific Antigen, MOC31 and Ber-EP4. Several monoclonal antibodies have been raised against Ep-CAM, many of which have been described as tumour specific molecules on carcinomas. Ep-CAM is a Type 1 transmembrane glycoprotein. It is expressed on the basolateral membrane of cells by the majority of epithelial tissues, with the exception of adult squamous epithelium and some specific epithelial cell types including hepatocytes and gastric epithelial cells. Ep-CAM expression has been reported to be a possible marker of early malignancy, with expression being increased in tumour cells, and de novo expression being seen in dysplastic squamous epithelium

Store at +4 degree C.

DO NOT FREEZE.

This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of dispatch.

34,932 Da

Chromosome: 2; NC_000002.11 (47596287..47614167). Location: 2p21

185535

ModBase 3D Structure for P16422

HT29 carcinoma cell line

Spleen cells from immunised BALB/c mice were fused with cells of a mouse myeloma cell line.

Purified IgG prepared by affinity chromatography

0.09% Sodium Azide
0.5% Bovine Serum Albumin

Phosphate buffered saline