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Reelin (RELN) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2135394

MBS2135394 is an antibody targeting RELN. Also known as APC_Cy7 Linked Monoclonal Antibody to Reelin (RELN). Reactive in Human, Pig. Host: Mouse. More details

$485 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Reelin (RELN), Monoclonal Antibody
Full Product Name
APC_Cy7 Linked Monoclonal Antibody to Reelin (RELN)
Product Gene Name
Product Synonym Names
RELN/Reelin; RL
Clonality
Monoclonal
Isotype
IgG2b Kappa
Clone Number
C15
Host
Mouse
Species Reactivity
Human, Pig
Form/Format
Liquid; 0.01M PBS, pH7.4, containing 0.05% Proclin300, 50% glycerol.
Purity/Purification
Protein A + Protein G affinity chromatography
Concentration
>=0.1mg/mL (Please refer to the vial label for the specific concentration.) (lot specific)
Specificity
The antibody is a mouse monoclonal antibody raised against RELN. It has been selected for its ability to recognize RELN in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 2 degree C to 8 degree C for frequent use, 20 degree C for 24 months
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: RELN Clone #C15 (MBS2139183)
APC-CY7 Conjugated Antibody: RELN Clone #C15 (MBS2135394)
Molecular Weight
384,093 Da
OMIM
U79716 mRNA
3D Structure
ModBase 3D Structure for P78509
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen Type
Prokaryotic Recombinant proteins/RP
Sequence of Immunogen
Glu3142~Pro3460
Conjugation
APC Cy7
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-RELN antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes for anti-RELN antibody
WB: 0.52ug/mL
IHC: 520ug/mL
ICC: 520ug/mL

Other Notes

Small volumes of anti-RELN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RELN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
reelin isoform a
NCBI Official Synonym Full Names
reelin
NCBI Official Symbol
RELN
NCBI Official Synonym Symbols
RL; ETL7; LIS2; PRO1598
UniProt Protein Name
Reelin
Protein Family
UniProt Gene Name
RELN
NCBI Protein Information
reelin

NCBI Summary for RELN

This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for RELN

Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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