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CD84 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS213727

Mouse anti Human CD84 antibody, clone CD84.1.21 recognizes the human CD84 cell surface antigen, a highly glycosylated cell surface antigen of 64-82kD. CD84 is predominantly expressed by B lymphocytes, monocytes and macrophages, although lower levels of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CD84, Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN CD84:RPE
Product Gene Name
anti-CD84 antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
CD84.1.21
Host
Mouse
Form/Format
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised
Preparation and Storage
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.
Molecular Weight
24,025 Da
OMIM
604513
3D Structure
ModBase 3D Structure for Q9UIB8
Reconstitution
Reconstitute with 1 ml distilled water
Perservative Stabilisers||0.09% Sodium Azide
1% Bovine Serum Albumin
5% Sucrose
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen
Mouse pre-B cell line 300.19 transfected with CD84 cDNA.
Fusion Partners||Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS-1 myeloma cell line.
Buffer Solution||Phosphate buffered saline
Target Species
Human
Applications Tested/Suitable for anti-CD84 antibody
Flow cytometry (FC/FACS)
Application Notes for anti-CD84 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood.
Flow Cytometry: Maximum Dilution: Neat

Testing Data of anti-CD84 antibody

Staining of human peripheral blood monocytes with Mouse anti Human CD84: RPE
Mouse Anti-CD84 Monoclonal Antibody – Cat# MBS213727

Testing Data of anti-CD84 antibody

Staining of human peripheral blood monocytes with Mouse anti Human CD84 (MBS212511)
Mouse Anti-CD84 Monoclonal Antibody, Testing Data – Cat# MBS213727

Other Notes

Small volumes of anti-CD84 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD84 purchase

MBS213727 is an antibody targeting CD84. Also known as MOUSE ANTI HUMAN CD84:RPE. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD84. It may not necessarily be applicable to this product.

NCBI GI #
296434285
NCBI GeneID
8832
NCBI Accession #
NP_001171808.1
UniProt Primary Accession #
Q9UIB8
UniProt Secondary Accession #
O15430; O95266; O95660; Q5H9R1; Q6FHA8; Q8WLP1; Q8WWI8; Q9UF04; Q9UIB6; B2R8T1; B7Z3R8
UniProt Related Accession #
Q9UIB8
GenBank Nucleotide #
NM_001184879.1
NCBI Official Full Name
SLAM family member 5 isoform 1
NCBI Official Synonym Full Names
CD84 molecule
NCBI Official Symbol
CD84
NCBI Official Synonym Symbols
LY9B; hCD84; mCD84; SLAMF5
UniProt Protein Name
SLAM family member 5
UniProt Synonym Protein Names
Cell surface antigen MAX.3; Hly9-beta; Leukocyte differentiation antigen CD84; Signaling lymphocytic activation molecule 5; CD_antigen: CD84
Protein Family
SLAM family
UniProt Gene Name
CD84
UniProt Synonym Gene Names
SLAMF5
UniProt Entry Name
SLAF5_HUMAN
NCBI Protein Information
SLAM family member 5; CD84 antigen (leukocyte antigen); cell surface antigen MAX.3; hly9-beta; leucocyte differentiation antigen CD84; leukocyte antigen CD84; leukocyte differentiation antigen CD84; signaling lymphocytic activation molecule 5

NCBI Summary for CD84

This gene encodes a membrane glycoprotein that is a member of the signaling lymphocyte activation molecule (SLAM) family. This family forms a subset of the larger CD2 cell-surface receptor Ig superfamily. The encoded protein is a homophilic adhesion molecule that is expressed in numerous immune cells types and is involved in regulating receptor-mediated signaling in those cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
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UniProt Comments for CD84

CD84: Plays a role as adhesion receptor functioning by homophilic interactions and by clustering. Recruits SH2 domain- containing proteins SH2D1A/SAP. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cell surface; Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 1q24

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: protein binding; receptor activity

Biological Process: defense response; homophilic cell adhesion; blood coagulation; leukocyte migration
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Research Articles on CD84

1. up-regulated in Kawasaki disease arteriopathy

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CD84 antibody

 Products by Pathway  Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram

Diseases associated with anti-CD84 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >3 publications with CD84 and Inflammation
 Neoplasms, Experimental Antibodies  >2 publications with CD84 and Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >2 publications with CD84 and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >2 publications with CD84 and Nervous System Diseases
 Necrosis Antibodies  >2 publications with CD84 and Necrosis
 Adenocarcinoma Antibodies  >1 publications with CD84 and Adenocarcinoma
 Liver Neoplasms Antibodies  >1 publications with CD84 and Liver Neoplasms
 Disease Models, Animal Antibodies  >1 publications with CD84 and Disease Models, Animal

Organs/Tissues associated with anti-CD84 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >49 publications with CD84 and Blood
 Bone Antibodies  >10 publications with CD84 and Bone
 Spleen Antibodies  >7 publications with CD84 and Spleen
 Lymph Node Antibodies  >5 publications with CD84 and Lymph Node
 Lymph Antibodies  >4 publications with CD84 and Lymph
 Tonsil Antibodies  >4 publications with CD84 and Tonsil
 Pharynx Antibodies  >3 publications with CD84 and Pharynx
 Liver Antibodies  >3 publications with CD84 and Liver
 Testis Antibodies  >1 publications with CD84 and Testis
 Intestine Antibodies  >1 publications with CD84 and Intestine
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