Mouse Anti-CD101 Monoclonal Antibody – Cat# MBS213754

Staining of human peripheral blood granulocytes with Mouse anti Human CD101: RPE

CD101 Antibody – Mouse Monoclonal

Name: CD101 Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS213754
Price: 590 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS213754

Mouse anti Human CD101 antibody, clone BB27 recognizes human CD101. CD101 is a 140kDa homodimeric cell surface glycoprotein expressed primarily by monocytes, granulocytes, dendritic cells and activated T lymphocytes. Studies suggest that CD101 plays a major… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CD101, Monoclonal Antibody

Full Product Name

MOUSE ANTI HUMAN CD101:RPE

Product Gene Name

anti-CD101 antibody

Clonality

Monoclonal

Isotype

IgG1

Clone Number

BB27

Host

Mouse

Form/Format

Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised

Preparation and Storage

Prior to reconstitution store at 4 degree C. Following reconstitution store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.

Molecular Weight

115,109 Da

OMIM

604516

3D Structure

ModBase 3D Structure for Q93033

Reconstitution

Reconstitute with 1 ml distilled water
Perservative Stabilisers||0.09% Sodium Azide
1% Bovine Serum Albumin
5% Sucrose
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen

Human thymic clone B12
Buffer Solution||Phosphate buffered saline

Target Species

Human

Applications Tested/Suitable for anti-CD101 antibody

Flow cytometry (FC/FACS)

Application Notes for anti-CD101 antibody

Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cell in 100ul.
Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/5

Other Notes

Small volumes of anti-CD101 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD101 purchase

MBS213754 is an antibody targeting CD101. Also known as MOUSE ANTI HUMAN CD101:RPE. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD101. It may not necessarily be applicable to this product.

NCBI GI #

368711306

NCBI GeneID

9398

NCBI Accession #

NP_001243035.1

UniProt Primary Accession #

Q93033

UniProt Secondary Accession #

Q15856

UniProt Related Accession #

Q93033

GenBank Nucleotide #

NM_001256106.2

NCBI Official Full Name

immunoglobulin superfamily member 2 isoform 1

NCBI Official Synonym Full Names

CD101 molecule

NCBI Official Symbol

CD101

NCBI Official Synonym Symbols

V7; IGSF2; EWI-101

UniProt Protein Name

Immunoglobulin superfamily member 2

UniProt Synonym Protein Names

Cell surface glycoprotein V7; Glu-Trp-Ile EWI motif-containing protein 101; EWI-101; CD_antigen: CD101

Protein Family

Immunoglobulin superfamily

UniProt Gene Name

CD101

UniProt Synonym Gene Names

EWI101; IGSF2; V7; IgSF2; EWI-101

UniProt Entry Name

IGSF2_HUMAN

NCBI Protein Information

immunoglobulin superfamily member 2; cell surface glycoprotein V7; glu-Trp-Ile EWI motif-containing protein 101; leukocyte surface protein

UniProt Comments for CD101

IGSF2: Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3- induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 1p13

Cellular Component: integral to membrane; plasma membrane

Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides

Biological Process: cell surface receptor linked signal transduction; metabolic process; positive regulation of myeloid leukocyte differentiation

Research Articles on CD101

1. Single Nucleotide Polymorphism in CD101 gene may be associated with pancreatic cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD101 antibody

Reference Product	PubMed Publications
CD81 antibody	>2 publications with CD101 and CD81
IGSF3 antibody	>2 publications with CD101 and IGSF3
CD58 antibody	>1 publications with CD101 and CD58
CD9 antibody	>1 publications with CD101 and CD9

Diseases associated with anti-CD101 antibody

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>9 publications with CD101 and Immune System Diseases
Inflammation Antibodies	>6 publications with CD101 and Inflammation
Necrosis Antibodies	>1 publications with CD101 and Necrosis

Organs/Tissues associated with anti-CD101 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>20 publications with CD101 and Blood
Spleen Antibodies	>2 publications with CD101 and Spleen
Bone Marrow Antibodies	>1 publications with CD101 and Bone Marrow
Lung Antibodies	>1 publications with CD101 and Lung