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Glutathione Peroxidase 3, Plasma (GPX3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2139672

MBS2139672 is an antibody targeting GPX3. Also known as Polyclonal Antibody to Glutathione Peroxidase 3, Plasma (GPX3). Reactive in Mouse. Host: Rabbit. More details

$215 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glutathione Peroxidase 3, Plasma (GPX3), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Glutathione Peroxidase 3, Plasma (GPX3)
Product Gene Name
Product Synonym Names
GPX3/Glutathione Peroxidase 3, Plasma; GSHPX3; GPxP; GSHPxP; GPXP; Plasma glutathione peroxidase; Extracellular glutathione peroxidase
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Liquid; 0.01M PBS, pH7.4, containing 0.05% Proclin300, 50% glycerol.
Purity/Purification
Antigenspecific affinity chromatography followed by Protein A affinity chromatography
Concentration
500ug/mL (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against GPX3. It has been selected for its ability to recognize GPX3 in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 2 degree C to 8 degree C for frequent use, 20 degree C for 24 months
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: GPX3 (MBS2139672)
APC-CY7 Conjugated Antibody: GPX3 (MBS2135636)
Matching Pairs
Unconjugated Antibody: GPX3 (MBS2139672)
PE Conjugated Antibody: GPX3 (MBS2135637)
Molecular Weight
25,424 Da
3D Structure
ModBase 3D Structure for P46412
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen Type
Prokaryotic Recombinant proteins/RP
Sequence of Immunogen
Arg3~Tyr72
Conjugation
Unconjugated

Product Categories/Family for anti-GPX3 antibody

ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-GPX3 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes for anti-GPX3 antibody
WB: 0.52ug/mL
IHC: 520ug/mL
ICC: 520ug/mL

Other Notes

Small volumes of anti-GPX3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPX3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
glutathione peroxidase 3
NCBI Official Synonym Full Names
glutathione peroxidase 3
NCBI Official Symbol
Gpx3
NCBI Official Synonym Symbols
GPx; EGPx; GSHPx-3; GSHPx-P; AA960521
UniProt Protein Name
Glutathione peroxidase 3
UniProt Synonym Protein Names
Plasma glutathione peroxidase; GPx-P; GSHPx-P
UniProt Gene Name
Gpx3
UniProt Synonym Gene Names
GPx-3; GSHPx-3; GPx-P; GSHPx-P
UniProt Entry Name
GPX3_MOUSE
NCBI Protein Information
glutathione peroxidase 3; GPx-3; GPx-P; plasma GPx; extracellular GPx; plasma glutathione peroxidase

NCBI Summary for GPX3

This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This gene is highly expressed in the kidney where it may play a role in protecting the kidney from oxidative damage. [provided by RefSeq, Feb 2012]
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UniProt Comments for GPX3

GPX3: Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. Belongs to the glutathione peroxidase family.

Protein type: Secreted, signal peptide; Secreted; Other Amino Acids Metabolism - glutathione; Lipid Metabolism - arachidonic acid; Oxidoreductase; EC 1.11.1.9

Cellular Component: extracellular space; extracellular region

Molecular Function: selenium binding; peroxidase activity; glutathione binding; oxidoreductase activity; glutathione peroxidase activity

Biological Process: glutathione metabolic process; hydrogen peroxide catabolic process; response to oxidative stress; protein homotetramerization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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